Biomedical subjects

Qi Jia

Publications and source records attributed to Qi Jia.

4 recordsLinked to original sources

PubMed2007

Emergency endovascular repair of iliac artery rupture caused by post-stenting angioplasty with an endograft.

Iliac artery rupture is a rare complication of post-stenting angioplasty and can lead to massive life-threatening haemorrhage. Conventional surgery can not repair the damaged vessel easily and may cause substantial blood loss and high operative morbidity and mortality. We report our experience with a self-expanding covered endoprosthesis for endovascular repair of the rupture of an iliac artery caused by stenting angioplasty.

Aged, 80 and over↗

PubMed2006

Coumestans from Hedysarum multijugum.

Ten coumestans were isolated from the roots of Hedysarum multijugum. Their structures were elucidated as the new hedysarimcoumestans A-H (1-8), 1,3,9-trimethoxycoumestan (9), and aureol (10), on the basis of spectroscopic analyses.

Coumarins↗

PubMed2002

Modulation of melanogenesis by aloesin: a competitive inhibitor of tyrosinase.

Aloesin, [2-acetonyl-8-beta-d-glucopyranosyl-7-hydroxy-5-methylchromone], a compound isolated from the Aloe plant, is shown in these studies to modulate melanogenesis via competitive inhibition of tyrosinase. Aloesin inhibits purified tyrosinase enzyme and specifically inhibits melanin production in vitro. Enzyme kinetics studies using normal human melanocyte cell lysates and cell-based melanin production demonstrated that aloesin is a competitive inhibitor of tyrosinase from mushroom, human and murine sources. Tyrosine hydroxylase and 3,4-dihydroxyphenylalanine (DOPA) oxidase activities of tyrosinase from normal human melanocyte cell lysates were inhibited by aloesin in a dose dependent manner. In a percutaneous absorption study a finite dose of aloesin penetrated the skin slowly and was recovered primarily in the surface wash. Aloesin shows promise as a pigmentation-altering agent for cosmetic or therapeutic applications.

Absorption↗

PubMedDate not supplied

Headspace gas chromatography-flame ionization detector method for organic solvent residue analysis in dietary supplements.

An analytical method has been developed for the identification and quantification of 20 organic solvent residues in dietary supplements. The method utilizes a headspace sampler interfaced with gas chromatography and flame ionization detection. With split injection (5:1) and a DB-624 column, most of the organic solvents are separated in 9 min. The method has been validated and was found to be relatively simple and fast, and it can be applied to most common organic solvent residues. With the mass detector, the method was able to identify organic solvents beyond the 20 standards tested.

Chromatography, Gas↗