Biomedical subjects

QiNeng Ping

Publications and source records attributed to QiNeng Ping.

2 recordsLinked to original sources

PubMed2006

Interconversion kinetic studies of betamethasone acetate polymorphs in water.

This study assessed the effect of polymers on the transformation of polymorphs of betamethasone acetate (BA) when suspended in water. The results showed that the polymers, in particular HPMC E5, retarded the transition of the forms Ialpha and Ibeta. However, the form Ialpha, as the metastable form, with the aid of HPMC E5, was preferred for BA suspension preparation through kinetic studies, while the form Ibeta was not suitable due to its instability in water.

Betamethasone↗

PubMed2005

Interconversion studies of betamethasone acetate polymorphs.

The polymorph interconversions of Betamethasone Acetate (BA) were studied under various pharmaceutical conditions, such as grinding, heating and suspending in water, based on differential scanning calorimetry, thermogravimetric analysis, and X-ray powder diffraction. There existed enantiotropic relationships between the three polymorphs of BA, which were named form II, Ialpha, and Ibeta work, respectively. It was concluded that form II was the most stable form when suspended in water.

Betamethasone↗