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Biomedical subjects

Qing Hang Zhang

Publications and source records attributed to Qing Hang Zhang.

4 recordsLinked to original sources

Finite element analysis of head-neck kinematics during motor vehicle accidents: analysis in multiple planes.

In this study, a detailed three-dimensional head-neck (C0-C7) finite element (FE) model developed previously based on the actual geometry of a human cadaver specimen was used. Five simulation analyses were performed to investigate the kinematic responses of the head-neck complex under rear-end, front, side, rear- and front-side impacts. Under rear-end and front impacts, it was predicted that the global and intervertebral rotations of the head-neck in the sagittal plane displayed nearly symmetric curvatures about the frontal plane. The primary sagittal rotational angles of the neck under direct front and rear-end impact conditions were higher than the primary frontal rotational angles under other side impact conditions. The analysis predicted early S-shaped and subsequent C-shaped curvatures of the head-neck complex in the sagittal plane under front and rear-end impact, and in the frontal plane under side impact. The head-neck complex flexed laterally in one direction with peak magnitude of larger than 22 degrees and a duration of about 130 ms before flexing in the opposite direction under both side and rear-side impact, compared to the corresponding values of about 15 degrees and 105 ms under front-side impact. The C0-C7 FE model has reasonably predicted the effects of impact direction in the primary sagittal and frontal segmental motion and curvatures of the head-neck complex under various impact conditions.

Accidents, Traffic↗

Effects of bone materials on the screw pull-out strength in human spine.

A three-dimensional finite element model simulating the threaded connections including detailed helix curve for the bone and surgical screw was constructed. Validation of the FE model was conducted by comparing the predicted screw pull-out strength in different foam materials against experimental study. The FE model was then further analyzed to investigate the interaction of bone material and purchase length on the screw pull-out strength. The results show that failure of the connection was due to bone shearing which occurred along a cylindrical surface determined by the outer perimeter of the screw. The cortical shell resists around 50% of the pull-out strength for a screw of 4mm in major diameter and 22 mm in length. The effects of purchase length on the pull-out strength were different for different bone material. It is the bone material that determines the stability of the inserted surgical screw. The significance of the purchase length on the pull-out strength of cortical screw will be much lower than that in cancellous bone screw.

Bone Screws↗

Development and validation of a CO-C7 FE complex for biomechanical study.

In this study, the digitized geometrical data of the embalmed skull and vertebrae (C0-C7) of a 68-year old male cadaver were processed to develop a comprehensive, geometrically accurate, nonlinear C0-C7 FE model. The biomechanical response of human neck under physiological static loadings, near vertex drop impact and rear-end impact (whiplash) conditions were investigated and compared with published experimental results. Under static loading conditions, the predicted moment-rotation relationships of each motion segment under moments in midsagittal plane and horizontal plane agreed well with experimental data. In addition, the respective predicted head impact force history and the S-shaped kinematics responses of head-neck complex under near-vertex drop impact and rear-end conditions were close to those observed in reported experiments. Although the predicted responses of the head-neck complex under any specific condition cannot perfectly match the experimental observations, the model reasonably reflected the rotation distributions among the motion segments under static moments and basic responses of head and neck under dynamic loadings. The current model may offer potentials to effectively reflect the behavior of human cervical spine suitable for further biomechanics and traumatic studies.

Cervical Vertebrae↗

Finite element analysis of moment-rotation relationships for human cervical spine.

A comprehensive, geometrically accurate, nonlinear C0-C7 FE model of head and cervical spine based on the actual geometry of a human cadaver specimen was developed. The motions of each cervical vertebral level under pure moment loading of 1.0 Nm applied incrementally on the skull to simulate the movements of the head and cervical spine under flexion, tension, axial rotation and lateral bending with the inferior surface of the C7 vertebral body fully constrained were analysed. The predicted range of motion (ROM) for each motion segment were computed and compared with published experimental data. The model predicted the nonlinear moment-rotation relationship of human cervical spine. Under the same loading magnitude, the model predicted the largest rotation in extension, followed by flexion and axial rotation, and least ROM in lateral bending. The upper cervical spines are more flexible than the lower cervical levels. The motions of the two uppermost motion segments account for half (or even higher) of the whole cervical spine motion under rotational loadings. The differences in the ROMs among the lower cervical spines (C3-C7) were relatively small. The FE predicted segmental motions effectively reflect the behavior of human cervical spine and were in agreement with the experimental data. The C0-C7 FE model offers potentials for biomedical and injury studies.

Biomechanical Phenomena↗