Biomedical subjects

Qing-wen Lü

Publications and source records attributed to Qing-wen Lü.

3 recordsLinked to original sources

PubMed2006

[A preliminary study of beam weight optimization of intensity-modulated radiation therapy with genetic algorithm].

UNLABELLED: To study the method for dose calculation and beam weight optimization of intensity-modulated radiation therapy (IMRT). METHODS: The IMRT dose calculation model based on two-dimensional convolution was constructed, the program of dose calculation and beam weight optimization with genetic algorithm was written with Visual c#.Net, and the optimization results were analyzed. RESULTS: Genetic algorithm optimization of beam weights can produce highly conformal dose distributions within a clinically acceptable computation time. CONCLUSION: Genetic algorithm is valid and efficient in IMRT beam weight optimization, which may facilitate IMRT treatment planning.

Algorithms↗

PubMed2005

[A new method for static intensity-modulated radiation therapy].

OBJECTIVE: To develop a new method for static intensity-modulated radiation therapy (IMRT) possible for implementation in smaller hospitals by incorporating accurate location equipments and treatment planning system in the available equipments for general radiotherapy. METHODS: Based on the techniques of conformal radiotherapy, a new split method for fabricating the three-dimensional physical compensator was developed to achieve IMRT. RESULTS: Experiment with the new method showed that the fabricated compensator could achieve good match between the high dosage shape in the target area and the dimensions of the tumor, and allowed adjustment of the dosage distribution according to the therapeutic requirement. CONCLUSION: This simple and feasible method allows cost-effect application of IMRT in smaller hospitals.

Humans↗

PubMed2003

[A study on the relation between the location of brain damage and agraphia of Chinese].

OBJECTIVE: To investigate the relation between the location of brain damage and Chinese agraphia. METHODS: Aphasia Battery of Chinese (ABC) and Chinese Agraphia Battery (CAB) were used to examine the ability of oral language and writing. Different types of aphasia and agraphia were detected. Computerized image-processing technology was used to standardize and reconstruct the skull CT/MRI images. The results substracted from the normal controls were shown directly. RESULTS: 48 patients had lesions on the left brain among them 30 were aphasic and 32 were agraphic. 15 had lesions on the right brain, among them 3 were aphasic and agraphic. The image-processing results showed that the nidi of aphasic agraphia located on the left deep albae of frontal and parietal lobe, the nidi of persistent agraphia located on the posterior parts of the left 1st and 2nd gyrus of frontal lobe and the nidi of mirror agraphia were dispersed near the left basal ganglion and thalamus. CONCLUSIONS: It is found that there is a relationship between Chinese agraphia and the location of brain damage. Some parts may be responsible for some special writing ability.

Adult↗