Biomedical subjects

R A Attia

Publications and source records attributed to R A Attia.

5 recordsLinked to original sources

PubMed1995

Importance of E. histolytica antigen in serodiagnosis and follow up of patients with amoebic liver abscess.

This study is composed of a community based study and a hospital based study. The community based study was conducted on 200 apparently healthy individuals randomly chosen from rural areas. They were examined clinically, sonographically and parasitologically for E. histolytica cysts and by ELISA for circulating amoebic antigen. They were negative for antigenaemia at 1/16 which was considered the diagnostic titre of amoebic hepatitis. The hospital based study was carried out on 27 patients suffering from amoebic liver abscess (ALA). Circulating amoebic antigen was detected in 66.66% of them before treatment which decreased to 14.82% two months after treatment. There was no significant association between the diameter of the abscess and the level of circulating amoebic antigen. It was concluded that the circulating amoebic antigen may be useful for the diagnosis and follow up of amoebic liver abscess patients.

Adolescent↗

PubMed1995

Toxoplasma IgG. & IgM. antibodies. A case control study.

This study includes 62 cases of spontaneous abortions and 75 cross matched non pregnant multiparous women as controls. Micro-ELISA test was done to measure Toxoplasma IgM & IgG antibodies. Out of 62 aborting women, 26 gave positive anti-Toxoplasma IgG antibodies, more than 45 Eu/ml and 28 gave positive anti-Toxoplasma IgM antibodies, more than 40 Eu/ml without statistical significant difference. There was a significant difference between aborting women and the controls as regards IgG & IgM antibodies. IgG antibodies, showed statistical significant difference between those with no history of abortions or I-2 abortions versus those with 3 or more abortions. The infection was more among aborting women in rural than urban areas whom suffered poor hygienic measures and awareness about the mode of transmission of Toxoplasma infection. The results were discussed.

Abortion, Spontaneous↗

PubMed1994

Some immunological studies on amoebiasis.

Studies of immunoglobulins pattern in 64 patients with different clinical symptoms of amoebiasis revealed that IgG showed no rise in patients with acute amoebic dysentery and asymptomatic cyst passers, while it was significantly increased in patients with active hepatic amoebiasis. IgM, IgA and IgE were significantly increased in both acute amoebic dysentery and active hepatic amoebiasis, but no significant changes in asymptomatic cyst passers. ELISA (depended on level of IgG) was valid and reliable in diagnosis of active hepatic amoebiasis (100%), IHAT (depended on level of IgM) gave 72.7% and 46.9% in patients with acute amoebic dysentery and active hepatic amoebiasis respectively.

Amebiasis↗

PubMed1994

The relation between ABO blood groups, HLA typing and giardiasis in children.

A total of 455 children were chosen randomly and surveyed for giardiasis by stool examination using several techniques. A case control study design was adopted where 91 cases of giardiasis (symptomatic and asymptomatic) and 101 children giardiasis free were examined. ABO blood groups and HLA typing were investigated. It was concluded that blood group A was more susceptible to giardiasis especially asymptomatic form, while blood group B was less susceptible to giardiasis. On the other hand, there was no association between AB or O and giardiasis. But, there was a strong association between HLA A10, A11, B5, B7 and B17 phenotypes and symptomatic giardiasis and an association as well between HLA B7, B17, Bw14 and Bw40 and asymptomatic giardiasis.

ABO Blood-Group System↗

PubMedDate not supplied

Impact of the current National Bilharzia Control Programme on the epidemiology of schistosomiasis mansoni in an Egyptian village.

In a population-based study in the Nile Delta of Egypt, the modified Kato thick smear technique was used to study the epidemiology of Schistosoma mansoni. After 2 years of implementation of the National Bilharzia Control Programme by the Ministry of Health, the general prevalence dropped from 47.2% to 21.9%. The peak prevalence rate has shifted downwards in magnitude (40.4% compared to 72.1%) and backwards over the age scale (5-14 in contrast to 15-19 years age group). Redistribution of various infection grades has taken place. More than three-quarters (75.6%) of the infected individuals have light infections in contrast to only one-fifth (20%) 2 years ago. The mean egg count for the entire sample population has dropped significantly (P < 0.05) from 128 to 17 eggs/g stools with no significant difference between males and females. This positive impact can be attributed largely to the case finding and treatment component of the programme. However, the incidence rate remained nearly the same before and 2 years after implementation of the programme (18.7 and 18.1%, respectively). The non-changing high incidence rate indicates that the knowledge, attitude and practice (KAP) of the population concerning water contact have not yet changed. Insufficient improvement in environmental sanitation may be a contributing factor. Continuation of serious efforts in case finding and treatment is recommended, with special emphasis on schoolchildren. This should be coupled with an intensive health education programme.

Adolescent↗