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Biomedical subjects

R A Elliott

Publications and source records attributed to R A Elliott.

47 records · Page 3Linked to original sources
PubMed1977

Lateral scalp flaps for instant results in male pattern baldness.

A technique for reconstruction of the anterior hairline, with undelayed lateral scalp flaps, is presented. Unilateral and bilateral flaps have given excellent results in selected patients with a variety of balding patterns. The advantage of gaining instant hair of good density along the anterior hairline is one not provided by the free graft techniques. The continued high patient acceptance and the minimal morbidity encourage further clinical study of this method with cautious enthusiasm.

Adult↗
PubMed1976

Use of nasolabial skin flap to cover intraoral defects.

Several fresh surgical defects of the maxillary alveolus, palate, and tonsillar area, resulting from the excision of cancer, have been repaired in a single operation by pulling through an inferiorly-based nasolabial flap with a subcutaneous pedicle. Patient rehabilitation has been rapid.

Aged↗
PubMed1976

Dacryoscintigraph evaluation of the repaired lacrimal drainage system.

We have used dacryoscintigraphy to study the efficiency of the lacrimal system following the repair of a divided lower canaliculus in 4 children. This test has been reliable in evaluating lacrimal function and suggests that a canaliculus can be repaired and splinted satisfactorily. Our experience with dacryoscintigraphy confirms that it is a safe comfortable, and reliable method for studying the patency of the lacrimal drainage system.

Child, Preschool↗
PubMed1974

Comparison of the distribution of tobramycin and gentamicin in body fluids of dogs.

Tobramycin serum, thoracic lymph, renal lymph, and urine concentrations were measured in mongrel dogs after intravenously administered 5, 10, and 20 mg/kg doses. These were compared with intravenous gentamicin delivered at 5 and 20 mg/kg. Both drugs achieved similar concentrations in serum and thoracic lymph. At 20 mg/kg, tobramycin showed consistently higher renal lymph and urine concentrations than gentamicin. At 5 mg of tobramycin per kg, renal lymph and urine concentrations were higher than with gentamicin only within the 1st h after administration. Thereafter the difference was no longer significant. These data suggest that on the basis of distribution in the body fluids of dogs, tobramycin is a reasonable alternative to gentamicin.

Animals↗
PubMedDate not supplied

Cardiovascular effects of cannabinol during oral surgery.

Fifty-five clinical trials were conducted to determine the cardiovascular combined effects of stressful oral surgery and systemic cannabinols. In a first study, delta9-tetrahydrocannabinol (THC) was given IV as a premedicant and compared with diazepam and with a placebo. A classic dose-related tachycardia followed THC injection. The peak heart rate response of patients premedicated with 0.044 mg/kg THC was 24.1% higher (p less than 0.05) than the peak effect for a nonsurgerized control group, suggesting a synergistic effect between THC and surgical stress. A predisposition to syncopal hypotension followed THC premedication, and antiarrhythmic effects were observed after large doses. The injection of local anesthetic preparations containing epinephrine did not alter THC cardiovascular response. An apparent drug interaction was observed, however, in a second study, in patients given general anesthesia within 72 hours after smoking marijuana. These patients demonstrated sustained abnormal postoperative tachycardia when compared with control nonsmokers, an effect which may have resulted from an interaction between stored cannabinol metabolites and atropine administered as part of the anesthetic technic. It was concluded that THC had no particular advantage over diazepam or placebo as a premedicant. Further, THC altered the patients' adaptivity to stress and interacted undesirably with other anesthetic medications.

Adult↗