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R A Evsegneev

Publications and source records attributed to R A Evsegneev.

7 recordsLinked to original sources
PubMed1992

[Individual prognosis in endogenous affective and schizoaffective psychoses: clinical predictors].

The purpose of the work was to search for predictors for early individual prognosis of the clinical characteristics of affective and schizoaffective psychoses and forecasting treatment responses to the tricyclic antidepressants and prevention with lithium salts. 285 patients (190 with affective and 95 with schizoaffective pathology) were examined. The mean disease standing was about 15 years, the mean duration of the follow-up amounted to over 4 years. More than 40 clinical and therapeutic signs were taken into account on the whole. The data were processed by EC-1036 computer. A number of coefficients indicating the intensity of interrelations between the study signs were computed. Based on the magnitudes of the above coefficients, the lists of the clinical predictor signs and protector signs were compiled to be used in psychiatric practice.

Adult↗
PubMed1992

[Individual prognosis in endogenous affective and schizoaffective psychoses: biological predictors].

A study was made of the distribution of a complex of biological markers: HLA antigens, loci A and B, ABO blood groups, haptoglobin phenotypes, acetylator status, indicators of anthropometry and dermatoglyphics, and marital radius of the parents in 285 patients with affective and schizoaffective psychoses--representatives of the Byelorussian population. The mean time of the clinical follow-up was over 4 years. The magnitudes of relative risk (RR) were computed with regard to the indicated biological signs to estimate their relation to the disease and to some characteristics thereof: polarity of affective disorders, the type of the course, age of manifestation, the presence of homonomous hereditary aggravation, late outcome as well as the efficacy of tricyclic antidepressants and lithium prevention. The data obtained are discussed from the standpoint of their practical use.

ABO Blood-Group System↗
PubMed1989

[Dexamethasone test in the diagnosis and treatment of affective psychoses].

The results of dexamethasone test (DT) in patients with affective psychoses are presented. Of these, 61 were investigated in depressive state, 15 in mania, 28 in intermission. The control group consisted of 29 schizophrenic patients without affective symptoms, 15 reactive depressed and 42 healthy persons. The level of serum cortisol was determined using the competitive radioassay. The baseline cortisol levels were higher in endogenous depressions as compared to control with the degree of cortisol reduction in endogenous depression reduced against any other group. The DT sensitivity was 55.7% in endogenous depressions, 40.0% in mania and its specificity about 93%. The cases of pathological DT results were more frequently observed in the affective group with familial anamnesis of endogenous psychoses.

Bipolar Disorder↗
PubMed1987

[Features of the distribution of HLA-antigens among patients with endogenous psychoses].

Distribution of HLA antigens of A and B loci was studied in 200 schizophrenics, 77 patients with manic-depressive psychosis of different forms, and in 350 healthy individuals. The findings included a significant elevation in the levels of the B7 antigen in both groups of patients, of antigen B12 in individuals with paroxysmal schizophrenia as well as a decrease in the concentrations of antigen B35 in recurrent schizophrenia. Patients with monopolar manic-depressive psychosis showed increased content of antigen B14 and decreased levels of antigen B5. The data obtained confirm heterogeneity of endogenic psychoses with regard to this sign.

Adult↗
PubMed1983

[Anorexia nervosa as a manifestation of endogenous depression in puberty].

Possible interrelation between anorexia nervosa and affective pathology is discussed. The authors present an analysis of clinical observations where the anorexia nervosa syndrome was developing in the presence of endogenous circulatory depression. It is noted that in some cases of latent depression, this syndrome may present the most prominent feature in the clinical picture of the disease, which makes its diagnosis and treatment rather difficult. Differential diagnostic signs permitting the differentiation between "depressive" anorexia nervosa and its other nosologic variants are discussed.

Adolescent↗