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Biomedical subjects

R A Goepp

Publications and source records attributed to R A Goepp.

At least 19 recordsLinked to original sources
PubMed1983

Diurnal variation of DNA synthesis in premalignant hamster cheek pouch.

The right cheek pouch of hamsters was painted twice a week with DMBA for 4 and 7 weeks in different groups. It was found that there were diurnal rhythms and non-random distributions of DNA synthesis and mitotic events in DMBA-treated hamster-cheek-pouch epithelium. The degree of these changes was markedly greater than the changes in non-treated control pouches. The finding of cluster formation was described as 'symphokinesis', the non-random grouping of basal cells with synchronous DNA cycles during tissue growth.

9,10-Dimethyl-1,2-benzanthracene↗
PubMed1981

Atherosclerosis in the tongue of the rhesus monkey.

Atherosclerotic vascular lesions in rhesus monkey tongues were studied, in both induction and regression periods. Vascular lesions were induced by peanut oil and a combination of coconut oil and butter fat, which caused the rapid elevation of serum lipids of all the animals. Atherosclerotic lesions were found in the tongues of all animals on an atherogenic diet. Larger arteries were found to be more susceptible to the disease. During the regression period animals received either a low-fat, low-cholesterol diet with or without cholestyramine, or an atherogenic diet with cholestyramine. Regression of the disease was more significant in animals on a low-fat, low-cholesterol and cholestyramine diet. Lesions in larger arteries in the tongues appeared to respond to the treatment more rapidly.

Animals↗
PubMed1977

Thyroid radiation dose during panoramic and cephalometric dental x-ray examinations.

Radiation exposure from panoramic equipment can be reduced significantly by use of smaller film, adjustment of the beam height to the height of the smaller film, and careful positioning of patients. These techniques have no adverse effect on the quality of the diagnostic information needed in dentistry. In addition to describing methods of reducing exposures from panoramic machines, this study demonstrates that the use of a barrier collar during static, cephalometric examinations can appreciably reduce thyroid exposure. Since the objective is to obtain diagnostic information from the film without irradiating the thyroid, the application of a lead-impregnated collar is a minor inconvenience, easily borne by the patient and operator. It should be noted that the use of the collar during panoramic examinations affords little or no protection since the relative motion of the panoramic machine places the axis of movement inside the head and neck of the patient. While the evolution of diagnostic radiology may have reached a high level of technical refinement of equipment and film the clinician still must avoid unnecessary exposure for X-ray examinations and must carefully select the best type of examination to be used for each patient. For example, a complete panoramic examination to determine the position of a known unerupted third molar tooth is probably not an exercise of good judgment since other examinations, such as periapical, could yield the same information with less exposure. Decisions must be made with good judgment, value being placed on relative risks versus the benefits of diagnostic yield.

Adolescent↗
PubMed1977

Diurnal variation in epithelial cell population kinetics of young mouse tongue.

The purpose of this study was to determine if there was a diurnal variation in the DNA synthesis pattern of epithelial basal cells in the dorsum of the mouse tongue between infancy and preadult ages. The pattern of DNA synthesis in the basal cells of mouse tongue in 24-hour periods for different age groups was studied by isotope labeling and radioautography. A strong diurnal variation was found in the pattern of DNA synthesis with the degree of variation dependent on the age of the experimental groups.

Age Factors↗
PubMed1976

Mandibular histiocytosis X and acute lymphoblastic leukemia.

The occurrence together of two major distinct diseases in the oral area is relatively rare. In this report, a case is presented in which histiocytosis X was found to develop in a child with acute lymphoblastic leukemia. The nature of the differentiated histiocytoses is explored, and the possibility of the relationship between a lymphoproliferative and a histiocytic disease entity is investigated.

Child, Preschool↗