Sulindac treatment for familial polyposis coli.
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Biomedical subjects
Publications and source records attributed to R A Gonzaga.
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We report a case of transverse testicular ectopia. The patient previously had undergone an operation for a left inguinal hernia and the right testis was absent. Each testis was placed in its respective side but the right vas deferens traversed the left inguinal canal (a modified Ombrédanne operation).
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A family with Peutz-Jeghers syndrome is reported, colonic involvement having been demonstrated on several affected members. Of the 50 members of the family about whom we could get informations, 21 had the characteristic cutaneous lesions (and usually had had some manifestation of the intestinal disease). Our first patient had a colonic carcinoma, and we could detect at least another colonic carcinoma in the family. A third attained member of the family was known to have died from "throat cancer". The most frequent clinical manifestations of this family patients are intussusception related abdominal crisis of colicky pain and rectorrhagy. In Peutz-Jeghers syndrome, there is a slight increase in the risk of malignancy, and digestive cancer can arise from coexistent adenomas, from cancerous changes of hamartomas, or "de novo", i.e., appear on previously normal mucosa.
This is a case of a 5-month-old girl with massive rectal bleeding caused by a gastric duplication. Cyst heterotopic pancreas and pancreatic duplication, an association not previously reported were present. The peculiar clinical presentation was due to cyst perforation that had subsequently eroded the transverse colon. Coexistent gastric containing heterotopic pancreas and pancreatic duplications were probably produced as traction diverticular by an embryonic entoectodermal adhesions.