Fatal pneumococcal bacteremia in a vaccinated, splenectomized child.
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Biomedical subjects
Publications and source records attributed to R A Gordon.
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A 4-year-old boy with acute lymphoblastic leukemia in relapse with documented septicemia due to group C Streptococci (Streptococcus equisimilis) is described. The patient responded well to therapy with appropriate cytotoxic and antimicrobial agents. There is a general lack of recognition of the pathogenicity of group C Streptococci in man. The potential opportunistic nature of these organisms in immunocompromised hosts and the need for early recognition and appropriate treatment of such infection is emphasized.
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This study was designed to test whether oxygen toxicity results in retinal damage that could be documented by the technique of fluorescein angiography. Three squirrel monkeys lived in 100% oxygen environments for periods ranging from 50 to 117 hours. Two of the monkeys incurred damage as evidenced by early multifocal leakage and subsequent accumulation of dye in the retina. All monkeys survived the exposures and were followed for several weeks thereafter. The pathology appeared to be reversible since later angiograms were either normal, or approaching normality, when the animals were sacrificed. Subsequent histopathologic examination revealed no abnormalities.
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