Biomedical subjects

R A Jackel

Publications and source records attributed to R A Jackel.

5 recordsLinked to original sources

PubMed1995

Prolactin secretion following repetitive seizures.

We studied serum prolactin levels after 24 seizures occurring in eight subjects. Video-EEG intracranial monitoring confirmed temporal or frontal partial seizures. Seizure type, focus, and duration were similar for seizures with and without significant postictal prolactin elevations. The seizure-free interval (the time between seizures) varied considerably. Seizures occurring after longer seizure-free intervals (31.75 to 240 hours) showed robust prolactin responses. After shorter seizure-free intervals (1.07 to 25.42 hours), prolactin responses were reduced. This suggests that the amount of releasable prolactin is limited, depleted by seizures, or perhaps inhibited by prolactin feedback. Seizure-free intervals should be considered when interpreting prolactin levels.

Adult↗

PubMed1989

Computed EEG topography in acute stroke.

The potential for clinical application of computed EEG topography (CET) has been known since 1978. However, studies relating to the focal brain lesions are few. We have studied 19 cases of acute stroke involving the cerebral hemispheres. CET and EEG were recorded as soon as possible, usually within 1-3 days of onset. Repeat maps were recorded at 1 wk. Symptoms, neurologic exam, routine EEG and CT scan were compared with the CET of power spectral and flash evoked potential data. Statistical criteria were also applied. Good correlation was noted between CET and EEG and CT. Occasionally, CET was noted to provide information beyond EEG or CT. These early studies suggest a potential utility for CET in the early diagnosis of stroke.

Adolescent↗

PubMed1987

Computed EEG topography in epilepsy.

Computed EEG Topography (CET) of 74 cases of epilepsy demonstrates the potential utility of this method beyond that of the analog EEG for the quantification and localization of regions of epileptogenesis. For the detection and localization of focal epilepsy, CET was equal to or better than the EEG in 77 p. 100 of cases and provided more evidence of focal abnormality in 8.5 p. 100. The topography of spectral power and of early and late, extravisual, components of the averaged evoked potential to flash were abnormal in the region of interictal spike activity.

Adolescent↗

PubMed1986

Metastatic adenocarcinoma presenting as a one-and-a-half syndrome. Clinical, radiological, and pathological correlations.

The one-and-a-half syndrome, produced by a lesion in the tegmentum at the level of the pons, rarely has been reported as the result of a solitary metastasis. We report a case of adenocarcinoma of the lung metastatic to the pontine tegmentum with clinical, radiological, and pathological confirmation of the anatomy of this syndrome.

Adenocarcinoma↗

PubMedDate not supplied

Bicycling movements as a manifestation of complex partial seizures of temporal lobe origin.

Alternating movements of the limbs during a seizure, especially bicycling movements of the legs, are often taken as strong evidence for the psychogenic origin of seizure activity in an adult population. A recent review of pseudoseizure manifestations concluded that alternating limb movements were "highly characteristic of pseudoseizures." We report two adult patients with complex partial seizures of temporal lobe origin, confirmed by ictal video EEG recording, in whom bicycling movements were the prominent ictal manifestation. Bicycling occurred 5-30 s after ictal onset and lasted 15-30 s. Use of video EEG recording continues to increase our understanding of the wide range of behaviors which may occur in the course of an epileptic seizure, particularly complex partial seizures. Few absolute clinical criteria remain to distinguish epileptic seizures from pseudoseizures. These two cases and one other reported case clearly remove bicycling movements from that category.

Adult↗