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Biomedical subjects

R A Josephs

Publications and source records attributed to R A Josephs.

7 recordsLinked to original sources
PubMed2001

Liquorice consumption and salivary testosterone concentrations.

Liquorice consumption has been shown to substantially reduce serum testosterone concentration. An explanation for this result was that the active component in liquorice (glycyrrhizic acid) interfered with 17 beta-hydroxysteroid deyhydrogenase, which has been shown in vitro to catalyse the conversion of androstenedione to testosterone. We twice attempted to replicate this effect of liquorice but could not. We identified differences between our methods and those of the previous study and possible statistical anomalies (including inappropriate use of statistical tests) in the earlier report.

Adult↗
PubMed1996

Self-verification in clinical depression: the desire for negative evaluation.

Do clinically depressed individuals seek favorable or unfavorable information about the self? Self-verification theory makes the counterintuitive prediction that depressed individuals solicit feedback that confirms their negative self-views. To test this prediction, participants were classified on the basis of a structured clinical interview and self-report measures into high-esteem, low self-esteem, and depressed groups. All participants were offered a choice between receiving favorable or unfavorable feedback; 82% of the depressed participants chose the unfavorable feedback, compared to 64% of the low self-esteem participants and 25% of the high self-esteem participants. Additional evidence indicated that depressed individuals also failed to exploit fully an opportunity to acquire favorable evaluations that were self-verifying. The authors discuss how seeking negative evaluations and failing to seek favorable evaluations may help maintain depression.

Adult↗
PubMed1992

Protecting the self from the negative consequences of risky decisions.

Three experiments tested the idea that a motive to protect self-esteem (SE) from the threat of regret can influence decision making. Threat to SE was manipulated by varying whether people expected to know the outcome of their decisions. Study 1 showed that when Ss expected feedback about their decisions, only Ss low in SE made regret-minimizing choices. Study 2 showed that when Ss did not expect to know the outcome of their decisions, SE differences in choice strategies disappeared. Study 3 manipulated expectations about feedback on chosen and unchosen alternatives and showed that the more feedback that was expected, the more likely low but not high SE Ss were to make regret-minimizing choices. These studies suggest that people base decisions not only on objective attributes of choice alternatives, but also on the damage to SE that is perceived to result from a poor-decision outcome.

Adult↗
PubMed1992

Gender and self-esteem.

Where does self-esteem (SE) come from? Three experiments explored the idea that men's and women's SE arise, in part, from different sources. It was hypothesized that SE is related to successfully measuring up to culturally mandated, gender-appropriate norms--separation and independence for men and connection and interdependence for women. Results from Study 1 suggested that men's SE can be linked to a individuation process in which one's personal distinguishing achievements are emphasized. Results from Study 2 suggested that women's SE can be linked to a process in which connections and attachments to important others are emphasized. Study 3 demonstrated that failing to perform well on gender-appropriate tasks engendered a defensive, compensatory reaction, but only in subjects with high SE. These findings are discussed with regard to their implications for the structure and dynamics of the self.

Adult↗
PubMed1990

Alcohol myopia. Its prized and dangerous effects.

This article explains how alcohol makes social responses more extreme, enhances important self-evaluations, and relieves anxiety and depression, effects that underlie both the social destructiveness of alcohol and the reinforcing effects that make it an addictive substance. The theories are based on alcohol's impairment of perception and thought--the myopia it causes--rather than on the ability of alcohol's pharmacology to directly cause specific reactions or on expectations associated with alcohol's use. Three conclusions are offered (a) Alcohol makes social behaviors more extreme by blocking a form of response conflict. (b) The same process can inflate self-evaluations. (c) Alcohol myopia, in combination with distracting activity, can reliably reduce anxiety and depression in all drinkers by making it difficult to allocate attention to the thoughts that provoke these states. These theories are discussed in terms of their significance for the prevention and treatment of alcohol abuse.

Alcohol Drinking↗
PubMed1990

The two faces of alcohol myopia: attentional mediation of psychological stress.

Two studies provided evidence that alcohol's relationship to psychological stress is indirect and is mediated by the allocation of attention. Study 1 found that, as the attentional demands of a distracting activity increased, so did alcohol's reduction of anxiety. Study 2 replicated this effect and found that a highly demanding activity could reduce anxiety even without alcohol. This study further implicated the role of attention in anxiety reduction by demonstrating a relationship between changes in anxiety and response latency to a secondary monitoring task. Finally, in both experiments, intoxicated subjects who did not perform any activity showed an increase in anxiety. From these data, we argue that alcohol affects psychological stress, to an important degree, through its ability, in conjunction with ongoing activity, to affect the amount of attention paid to stressful thoughts.

Adaptation, Psychological↗