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Biomedical subjects

R A Kane

Publications and source records attributed to R A Kane.

At least 127 records · Page 7Linked to original sources

Peripancreatic lymph node enlargement in Hodgkin's disease, non-Hodgkin's lymphoma, and pancreatic carcinoma.

The distribution of enlarged lymph nodes in the upper abdomen and retroperitoneum were classified according to their relationship to the pancreas in 47 patients with non-Hodgkin's lymphoma; in nine patients with Hodgkin's disease; and in 40 patients with pancreatic carcinoma. Four patterns of lymph node enlargement were evident: (1) preaortic retropancreatic lymphadenopathy; (2) pancreaticosplenic lymphadenopathy; (3) isolated celiac and/or portal lymphadenopathy; and (4) diffuse extensive lymphadenopathy. Features differentiating lymphoma from primary pancreatic neoplasm are discussed.

Adult↗

Thyroid nodules: sonographic-pathologic correlation.

Sonographic patterns of thyroid disease were correlated with pathologic findings. Twenty-eight cadaver thyroid glands were prospectively examined with a high-resolution real-time ultrasound scanner. Ultrasound findings were correlated in detail with gross and microscopic findings. Ultrasound is very accurate in detecting architectural variation, adenomatous goiter, and solitary nodules. Ultrasound cannot distinguish benign from malignant nodules, but it can be used to measure changes in nodule size. Glandular asymmetry and multiple solid nodules must be present for confident diagnosis of adenomatous goiter; hemorrhage, necrosis, and calcific spherules may be present in varying amounts. Fibrous septae, dilated follicles, and vascular calcification are found in normal aging thyroid glands. Using these criteria, ultrasonography is very accurate in the diagnosis of adenomatous goiter.

Adenocarcinoma↗

Porcelain gallbladder: ultrasound and CT appearance.

Nine patients with calcification of the gallbladder wall (porcelain gallbladder) were analyzed by ultrasound and the appearance correlated with the CT, radiographic, clinical, and surgical findings. Three distinct patterns were identified: (a) a hyperechoic semilunar structure with acoustic shadowing posteriorly, simulating a stone-filled gallbladder devoid of bile, which was seen in 5 patients; (b) a biconvex , curvilinear echogenic structure with variable acoustic shadowing, seen in all 3 patients with carcinoma of the gallbladder; and (c) an irregular clump of echoes with posterior acoustic shadowing, seen in 1 patient. Potential pitfalls in the diagnosis of gallbladder calcification are presented, and the association between calcification and cancer is emphasized.

Aged↗

Assessing the outcomes of nursing-home patients.

This paper describes the development of multidimensional measures of nursing-home patients' functioning. The technique was designed to gather information directly from the patients, using demonstrated ability in place of self-report wherever possible. Six domains are tapped: physiologic, activities of daily living, affective, cognitive, social, and satisfaction. Test-retest reliability ranges from .59 for social interaction to .85 for affect. Validity was tested by replication on successive waves of data as well as discriminant and content validity.

Activities of Daily Living↗

Computed tomography in acute cholecystitis: new observations.

The computed tomographic CT findings in five patients with acute cholecystitis were analyzed. Common findings included thickening and nodularity of the gallbladder wall, cholelithiasis, and dilatation of the gallbladder lumen. Other more specific findings included poor definition of the gallbladder wall, pericholecystic fluid collections, and gas collections within the gallbladder wall. Most of the CT findings are suggestive but not pathognomonic, and correlation with the clinical, scintigraphic, and sonographic findings is necessary.

Acute Disease↗

Pseudocyst of the pancreas complicating distal splenorenal shunt. A report of three cases with successful percutaneous drainage.

Three cases of pseudocysts of the pancreas complicating the operative procedure of distal splenorenal shunt are reported. In all of these patients, gross changes in the pancreas, consistent with chronic pancreatitis were found. Attention is called to the possibility of this complication occurring in association with this particular operation, specifically, when it is carried out in patients who may prove to have a considerable degree of pancreatic and retroperitoneal fibrosis secondary to alcoholic pancreatitis. All three pseudocysts were satisfactorily managed by percutaneous drainage under ultrasonic control, which provided a very satisfactory alternative to surgical decompression.

Alcoholism↗