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Biomedical subjects

R A Krieger

Publications and source records attributed to R A Krieger.

3 recordsLinked to original sources

Efficient temporal probabilistic reasoning via context-sensitive model construction.

We present a language for representing context-sensitive temporal probabilistic knowledge. Context constraints allow inference to be focused on only the relevant portions of the probabilistic knowledge. We provide a declarative semantics for our language. We present a sound and complete algorithm for computing posterior probabilities of temporal queries, as well as an efficient implementation of the algorithm. Throughout we illustrate the approach with the problem of reasoning about the effects of medications and interventions on the state of a patient in cardiac arrest. We empirically evaluate the efficiency of our system by comparing its inference times on problems in this domain with those of standard Bayesian network representations of the problems.

Algorithms

Clinical simulation using context-sensitive temporal probability models.

We present a language for representing context-sensitive temporal probabilistic knowledge. Context constraints allow inference to be focused on only the relevant portions of the probabilistic knowledge. We provide a declarative semantics for our language and an implemented algorithm (BNG) that generates Bayesian networks to compute the posterior probabilities of queries. We illustrate the use of the BNG system by applying it to the problem of modeling the effects of medications and other interventions on the condition of a patient in cardiac arrest.

Artificial Intelligence

CO2 power-assisted hand-held syringe: better visualization during diagnostic and interventional angiography.

Recent technology has produced high-flow and large-lumen catheters as well as other angiographic accessories to enhance the visualization of the coronary arteries during diagnostic and percutaneous transluminal coronary angioplasty (PTCA) procedures. In spite of these technological advances, there are still many cases in which the quality of the coronary angiography could be significantly improved. This paper reports on a clinical evaluation of a hand-held power syringe. The syringe offers the ability to power inject contrast safely and effectively during routine angiograms as well as through guiding catheters with the balloon catheter present during PTCA. At the same time, control of the injection is equal to that associated with manual syringes.

Angiography