PubMed Health⌕ Search

Biomedical subjects

R A Loukota

Publications and source records attributed to R A Loukota.

At least 19 recordsLinked to original sources

Vascularisation of Norian CRS bone cement and its replacement by autologous bone when used for orbital reconstruction.

Various bone cements based on calcium phosphate have been used as adjuncts for repairing both the craniofacial and axial skeleton. Ideally these materials should provide initial strength and contour for the reconstruction, and be replaced over time by physiological absorption and bony deposition. Although there is evidence from animal models to support this, opportunities for human studies are rare. Here we offer clinical and histological evidence of this process.

Absorption↗

Subclassification of fractures of the condylar process of the mandible.

We present the definitions of various types of fracture of the condylar process, which have been adopted for the Strasbourg Osteosynthesis Research Group (SORG), in their Pan-European prospective randomised controlled trial into the management of such fractures. We think that this will assist people in their description of the various types of fracture of the condylar process.

Humans↗

Buccal mucosal grafts for urethroplasty: surgical technique and morbidity.

We present an outline of the surgical technique for harvesting free buccal mucosal grafts for urethroplasty in 23 patients and an assessment of morbidity at the donor site. Any problems were recorded, particularly injury to the lingual and mental nerves, symptoms of obstruction of the parotid duct, and trismus. There were four early (less than 6 weeks) complaints of mild trismus and one late complaint. All the grafts were successful.

Adult↗

Lack of tooth eruption following maxillary fracture: case report.

Aberrant tooth development following facial fractures is unusual. It is commonly reported that tooth buds involved in the line of a mandibular fracture will continue to develop normally and erupt sequentially. Few cases have been cited regarding developing teeth in the line of maxillary fractures. In the case reported, the normal growth and position of a maxillary third molar can be seen to be retarded at the position of a maxillary fracture, sustained by a child in the mixed dentition phase of dental development.

Accidental Falls↗

Orthodontic and orthognathic management of a patient with osteogenesis imperfecta and dentinogenesis imperfecta: a case report.

This case report describes a patient's severe Class III malocclusion, managed with a combination of orthodontic and orthognathic treatment. The medical history was complicated by osteogenesis imperfecta and dentinogenesis imperfecta. In addition the patient was a Jehovah's Witness. Patients with osteogenesis imperfecta carry an increased risk of perioperative haemorrhage, and this led to bimaxillary surgery being carried out as two discrete surgical episodes for the patient described. In addition, the risk of enamel fracture led to orthodontic bands being cemented on all teeth. In spite of the increased risks a successful outcome was achieved.

Adolescent↗

Melanotic neuroectodermal tumour of infancy: an immunohistochemical and ultrastructural study.

Two cases of melanotic neuro-ectodermal tumour of infancy (MNTI)--a rare neoplasm arising in the first year of life--are reported, with the results of immunohistochemical and ultrastructural examination. The tumours consisted of a biphasic cell population in a fibrous stroma. The small, darkly staining cells comprising the first population stained positively for synaptophysin, showing them to be neuroblasts, and the large epithelioid cells comprising the second cell population stained positively with the antibodies HMB-45 and NKI-Beteb, showing them to be melanocytes. Ultrastructural examination of the second case confirmed the biphasic nature of the tumour cells, with secretory granules and neurofilaments in the neuroblastic population, and melanosomes in the epithelioid population. These results add to the evidence supporting the neural crest origin of MNTI and confirm its formation from two distinct cell lines. Both cases have responded to local excision, with no recurrence more than a year after initial treatment.

Antigens, Neoplasm↗

Mechanical analysis of maxillofacial miniplates.

The effect of compression and tensile forces on different types of maxillofacial miniplates was measured, in both as supplied and after bending states. Tests showed all plates showed values of tensile force at failure in excess of that found in most clinical situations; twisting through 90 degrees about the long axis had little effect. In flatwise bending tests there was a wide scatter of values of bending stiffness and ultimate load, indicating that some plates may be stronger than necessary. Repeatedly bending the plates reduced their bending stiffness, particularly in the continuous holed plates, and increased their ultimate load to failure. Values of bending stiffness and ultimate load were much larger when bending in the edgewise direction, with large differences between manufacturers. The data generated in the current study may assist the surgeon in deciding which type of plate to select for a particular clinical situation.

Bone Plates↗