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Biomedical subjects

R A Niekel

Publications and source records attributed to R A Niekel.

4 recordsLinked to original sources

[Vomiting after the first trimester of pregnancy: an alarming symptom].

Nausea and vomiting are common problems of pregnancy. Three pregnant women, 27, 25 and 28 years of age, presented with vomiting in the third trimester. The causes appeared to be maternal small bowel volvulus, which was derotated after primary caesarean section, an ileocecal abscess, which was the first manifestation of Crohn's disease, and acute pyelonephritis, treated with cefuroxim. The second and third babies were born spontaneously; no maternal or foetal mortality occurred. Persistent vomiting after the first trimester of pregnancy should be considered an alarm symptom which always requires further investigation.

Abdominal Abscess↗

Low-dose streptokinase in the treatment of arterial graft occlusions.

During the past 24 months, 19 infrainguinal bypass graft occlusions occurring in 17 patients were treated with local infusions of streptokinase. The treated grafts included three venous femorocrural grafts and four venous and 13 Goretex femoropopliteal grafts. Infusion managed to restore flow completely in 10 grafts. Partial clot lysis occurred in three and no lysis in six grafts. All successful recanalisations occurred within 120 hours of the initiation of thrombolytic therapy. Despite three major complications and the development of two minor haematomas, with an overall success rate of 55% our results support the use of streptokinase in the management of occluded bypass grafts.

Acute Disease↗

Graded compression sonography in acute appendicitis.

Acute appendicitis never was a radiologically established diagnosis. A study on sonography in acute appendicitis was published recently in which in 89% of cases the inflamed appendix could be demonstrated by ultrasound, utilising 5 and 7.5 MHz intraoperative linear array transducers. Our study was started to evaluate the possibilities of a standard 7.5 MHz sector transducer in detecting acute appendicitis. In our study sonography was correctly diagnosed in 72% of cases, but it became apparent that with the larger format transducer used in our study the retrocaecal appendix could not be demonstrated in the majority of cases. The reliability of sonography in detecting acute appendicitis is not high enough to be used on a large scale but sonography can play a role in doubtful cases of suspected acute appendicitis.

Acute Disease↗