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R A PHILLIPS

Publications and source records attributed to R A PHILLIPS.

18 recordsLinked to original sources
PubMed1964

THE 1961 CHOLERA EPIDEMIC IN MANILA, REPUBLIC OF THE PHILIPPINES.

A pandemic of El-Tor-type cholera began in south-east Asia during 1961. Many members of the medical profession, as well as government officials and the public, were confused by the relationship between the disease caused by the El Tor organism and classic Asiatic cholera. The authors observed large numbers of cholera patients admitted to San Lazaro Hospital, Manila, early in the Philippine epidemic, and in the present communication they draw attention to certain clinical and epidemiological features of so-called El Tor cholera. The paper not only describes the patients and the epidemic, but also suggests some of the treatment needs during such an epidemic. No indication was found that the disease caused by the classic cholera vibrio is different from that which is designated the El Tor variant.

Cholera↗
PubMed1963

The patho-physiology of cholera.

Studies conducted by US Navy Medical Research personnel in Cairo in 1947, and subsequently in Dacca, Bangkok, Hong Kong and Manila, have delineated, for the first time, the water and electrolyte losses in this disease, and have demonstrated that the cholera stool approximates an isotonic solution with a low (0.1 g%) protein content. The potassium content approximates 15 mEq/litre and the HCO(3) (-) ion approximates 45 mEq/litre; the sodium and chloride concentrations are proportionately lower than their plasma values. The low protein content and other studies refute the idea that the cholera stool is a transudate. The 1958 studies in Bangkok postulated that the diarrhoea resulted from an inhibition of the active transport of sodium ion from gut lumen to plasma. Subsequently, the presence of such an inhibitor was found in stools of patients with Asiatic cholera (Bangkok and Dacca) and with cholera El Tor (Hong Kong and Manila).

Cholera↗
PubMed1962

Asiatic cholera.

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Cholera↗