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Biomedical subjects

R A Plezia

Publications and source records attributed to R A Plezia.

8 recordsLinked to original sources

Oral squamous-cell carcinoma within a white-sponge nevus.

A 59-year-old woman had thick plaques of leukoplakia on the tongue bilaterally. The condition was initially diagnosed by biopsy as a white-sponge nevus. A second biopsy of a suspicious area on the right side showed squamous-cell carcinoma two years later. It is speculated that prednisone therapy for steroid-dependent intrinsic asthma may have caused a loss of "immunologic surveillance," which permitted development of malignancy in a previously benign condition.

Carcinoma, Squamous Cell

Frozen autogenous mandible as an immediate replacement graft.

A study in animals was designed to examine the feasibility of grafting autogenous frozen mandible. Two groups of animals were used. In the first group, periosteum was elevated from the bone before resection. In the second group, the periosteum was removed with the resected specimen. Osteogenesis was shown by clinical, radiographic, fluorescence, and histologic studies in both groups of animals. The same technique was performed in nine humans with carcinomas that involved the mandible. The results were encouraging. We believe that immediate or delayed reconstruction with autogenous frozen mandible in a patient undergoing ablative surgery of the head and neck with involvement of the bone may offer the patient, as well as the surgeon, another acceptable treatment modality.

Animals

Office emergencies: an outline of causes, symptoms, and treatment.

Conscientious dental practitioners are aware of the increasing chances for medical emergencies to arise in the dental office. New treatment modalities and drugs have increased potential life spans, but have also presented greater responsibilities to the dentist for properly managing these patients. Additionally, widely diversified sources are available to the dentist for acquiring and assembling all necessary information to train his personnel and organize equipment and drugs so he is constantly ready to handle any emergency. We have attempted to give a simple, thorough outline that provides basic information on causes, symptoms, and treatment of major medical emergencies, but that in no way reflects the only means of treating the specific emergency. We feel the manner presented allows one to regiment his diagnosis and treatment rapidly and make modifications to the list as needed.

Acute Disease

Fiber optic surgical retractor.

A ramus retractor with a variable high-intensity light source has been designed. It offers access, direct high-intensity visibility, reliability, compactness, and sterilizability. We have used this modification for the past five years. It has allowed direct visibility and identification of structures in the surgical field without the use of cumbersome overhead surgical lights, headlights, or spotlights.

Fiber Optic Technology

Felty's syndrome.

The clinical and pathologic findings of Felty's syndrome are discussed. A case is presented which demonstrates the nonspecific inflammatory oral lesions commonly seen with this syndrome. The role of the dentist in relating these nonspecific lesions to the basic disease process is emphasized.

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