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Biomedical subjects

R A Rich

Publications and source records attributed to R A Rich.

6 recordsLinked to original sources

GABA(A) receptor beta2/beta3 subunit and GAD67 immunoreactivity in the trigeminal motor nucleus during early postnatal development.

GABA neurotransmission plays a role in brainstem circuitry responsible for jaw movements. We investigated the developmental relationship between terminals expressing GAD67 and GABA(A) receptor beta(2)/beta(3) subunit expression within the trigeminal motor nucleus. GAD67 immunoreactivity was intense throughout development. Neuropilar beta(2)/beta(3) immunoreactivity emerged during the 2nd postnatal week. Our data provide anatomical evidence for a GABAergic innervation of neonatal trigeminal motoneurons and suggest that beta(2)/beta(3) subunit expression is developmentally regulated in trigeminal motoneurons.

Animals↗

Hospital parking: analysis and master planning.

Providing adequate parking facilities has become a major concern for many health care institutions. By performing a demand analysis based on information provided here, hospitals can begin to address the issues of: number of spaces needed to serve their present and future parking needs, pooled vs. segregated parking areas, and distance from parking area to hospital entrance for each group of hospital users. Also presented are three other factors that must be considered when planning for parking facilities: traffic flow around the lot or structure, parking fees, and location of new spaces.

Facility Design and Construction↗

Effect of pinealectomy on fatty acid composition of rat brain myelin.

To determine whether the previously demonstrated decrease in rat brian myelin after pinealectomy is associated with an abnormality in myelin composition, 92 rat pups were subjected either to pinealectomy or sham-pinealectomy at 4 days of age. These animals, reared in diurnal lighting, were killed at 40 days of age, and their brains were individually subjected to myelin fatty acid analysis. In both sexes, all the significant differences, as determined by multivariate analysis of variance, were found in the long chain fatty acids (chain lengths of 16 carbons or more). It was also observed that in 5 of 6 instances in which a significant difference appeared in both sexes for the same fatty acid, the mean quantity of each of these fatty acids in the pinealectomized animals was neither consistently higher nor lower than the comparable sham-operated mean. These results suggest that neonatal pinealectomy in the rat alters the fatty acid composition of brain myelin.

Animals↗