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Biomedical subjects

R A van Oosterom

Publications and source records attributed to R A van Oosterom.

8 recordsLinked to original sources
PubMed1996

Monitoring and estimating concentrations of polychlorinated biphenyls, dioxins, and furans in cattle milk and soils of Rhine-Delta floodplains.

In the Rhine-Delta, accumulation of microcontaminants in floodplain foodwebs has received little attention in comparison with aquatic communities. Here, soil and cattle milk samples were taken from three floodplains and analyzed for polychlorinated biphenyls (PCBs), dibenzodioxins (PCDDs) and dibenzofurans (PCDFs). Based on 2,3,7, 8-tetrachlorodibenzodioxin equivalents, total PCDD and PCDF residues in milk did not exceed the quality standard of 0.006 microg/kg fat weight. This was still the case if non- and mono-ortho PCBs were added to the total. Yet, the floodplains investigated were only moderately polluted according to previous studies and one cannot exclude higher levels in milk from other floodplains. Bioconcentration ratios of milk fat vs soil organic matter were about 0.01 to 0.1 for persistent PCBs. These values are in accordance with a few literature data found for other persistent compounds. Yet, ratios are lower than expected from equilibrium partitioning. Ratios for PCDDs and PCDFs were even lower, possibly due to biotransformation.

Animals↗
PubMed1996

Isolation and characterisation of dog uropathogenic Proteus mirabilis strains.

Proteus mirabilis strains isolated from the urine of dogs with urinary tract infections, were characterised with respect to the production of haemolysin and fimbriae. In contrast to healthy dogs, P. mirabilis was also isolated in high numbers from the faeces of dogs suffering from recurrent urinary tract infections. Production of fimbriae was demonstrated by electron microscopy and the presence of genes for two different types of major fimbrial subunits (MR/P-like or UCA-like) was demonstrated by Southern hybridisation. These genes were absent in the Proteus vulgaris, Providentia rettgeri and Morganella morganii strains tested. All but one P. mirabilis strains were haemolytic and most strains produced fimbriae albeit in different amounts. The UCA fimbrial subunits from dog and human isolates have identical molecular weights and N-terminal sequences and are immunologically cross reactive. It was concluded that dog uropathogenic P. mirabilis strains are very similar to human uropathogenic P. mirabilis strains.

Amino Acid Sequence↗
PubMed1986

Pipemidic acid, a new treatment for recurrent urinary tract infection in small animals.

A new chemotherapeutic agent, pipemidic acid, was used to treat 14 dogs and 2 cats with recurrent urinary tract infection caused by multiresistent strains of Escherichia coli and Proteus spp. Bacterial culture of the urine after treatment revealed disappearance of the microorganisms in all patients. It is concluded that pipemidic acid is a promising chemotherapeutic agent for urinary tract infections caused by multiresistant E. coli and Proteus spp., with the condition that bacterial culture during the course of treatment is obligatory.

Animals↗
PubMed1985

Cystourethroscopy in the dog.

The cystourethroscopic examination with cold light cystoscopes forms an essential part of a complete urological examination and is useful for diagnostic as well as surgical procedures. The fast and non-invasive character of the procedure limits the inconvenience to the patient. With the rigid non-flexible scope its use is, however, limited to female dogs, unless in the male dog a urethro(s)tomy is performed.

Animals↗
PubMed1983

[A plainly apparent cause of urethral obstruction].

Some mariginal notes regarding possible forms of treatment are made with reference to acute urethral obstruction appearing in a male dog. Although this obstruction was due to a rare cause, the procedure adopted may serve as guidance in planning a scheme of treatment in common cases of urethral obstruction caused by urinary calculi in male dogs.

Animals↗