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Biomedical subjects

R Achatzy

Publications and source records attributed to R Achatzy.

30 records · Page 2Linked to original sources

[Experimental and clinical employment of an endovenous-myocardiac screwing electrode (author's transl)].

A common postoperative complication following transvenous endocardial pacemaker implantation is the dislodgement and displacement of the electrode. Following trial of a new endovenous-myocardiac screwing electrode in dogs we have tried this electrode since December 1976 on 105 patients, of which 84 cases were implanted primarily and 21 secondarily. The average stimulation threshold was 0.7 V at a pulse width of 1 ms. 6 patients had complications. By making a judicious use of this electrode the rate of electrode dislodgement can be reduced appreciably.

Adult↗

[Heart-lung machine for babies and infants. Development, experimental and clinical testing].

In order to offer the benefit of open heart surgery to the very early age of even new born babies small shaped extracorporeal circulation facilities has been devised and constructed encouraging now the surgeon to an early anatomical correction of congenital heart disease. This heart-lung-machine is equipped with a sophisticated saftey control guaranteeing either a constant flow or a pressure controlled perfusion. Prior to clinical use it has been tested in extensive experimental series including mock circulation and experiments on dogs. First clinical applications in open heart surgery have been successful.

Animals↗

[Compensatory mechanisms of haemolysis after surgery with the heart-lung-maschine (author's transl)].

In 20 patients, suffering from various diseases, the extent of haemolysis and the correlation between the rate of haemolysis and various mechanisms of erythrocyte damage in the course of open heart surgery was studied. We investigated haemotological parameters, electrolytes, lactate dehydrogenase before, and 1, 3, 5, and 7 days after operation. Besides free haemoglobin, haptoglobin and haemopexin were determined 5 and 15 minutes after starting perfusior with the heart-lung machine and after finishing. The best index of haemolysis was free haemoglobin in the serum. With increasing duration of perfusion the rate of haemolysis increased. Compensating mechanisms were postoperative increase of haptoglobin and haemopexin.

Cardiac Surgical Procedures↗

[Haptoglobin in the course of surgery with the heart lung machine (author's transl)].

In 20 patients, who underwent open heart surgery, the results of quantitavely and semi-quantitavely determined haptoglobin (hp) were evaluated. A rapid method (Rapi tex-Hp-Test, Behring-Werke) was used. Five minutes after the heart lung machine was cut off hp decreased slightly, and increased about 200% at the 4th day after operation, compared to the preoperative value. These changes were less pronounced in patients with prosthetic heart values. Blood transfusions did not influence the results. There is a significant correlation between the results of hp determined quantitatively and semi-quantitatively.

Adolescent↗