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Biomedical subjects

R Adovasio

Publications and source records attributed to R Adovasio.

At least 19 recordsLinked to original sources

An unusual complication of open aortic surgery: hemorrhage due to the iatrogenic rupture of a renal cyst.

The authors describe a clinical case of a retroperitoneal hemorrhage due to rupture of a voluminous renal cyst during a conventional open aortic surgery. Intraoperative trauma is to be considered the cause of bleeding. In most cases the clinical evolution of the patient is benign and conservative treatment is sufficient. Considering the incidence of renal cysts in patients ungergoing conventional aortic surgery, we want to emphasize this possible complication, that has only rarely been dealt with in the literature. We recommend evaluation of such patients in view of preoperative drainage of large cyst including injection of sclerosing agents.

Aged↗

Middle aortic syndrome: an atypical case--a case report.

This case concerns a 61-year-old woman presenting with middle aortic syndrome treated by an aortoaortic thoracoabdominal polytetrafluoroethylene bypass and a right renal Dacron bypass. The case was atypical because of the patient's advanced age at the time of clinical presentation.

Aorta, Thoracic↗

[Ischemic heart disease and postoperative mortality in major vascular surgery. An up-to-date diagnostic approach].

BACKGROUND: The aim of this study is to evaluate the efficacy the dobutamine stress echocardiography in predicting the perioperative cardiac risk of patients undergoing major vascular surgery. METHODS: Seventy-seven consecutive and not selected patients, undergoing a surgical treatment requiring aortic cross clamping, were assessed also with a transthoracic dobutamine stress echocardiography. With electrocardiographic and echocardiographic monitoring ventricular ischemia or wall motion abnormalities, 5 micrograms/kg per min of chlorhydrate dobutamine for 5 minutes were infused, followed by other 10 micrograms/kg per min increased up to 40 micrograms/kg per min. During the last 4 minutes 0.25 mg of atropin were infused increasingly up to 1 mg. RESULTS: Of all these patients, 26 had a stress ischemia but only 4 cases underwent a coronary angiography and only 2 of these underwent a preventive myocardial revascularization. Due to poor cardiac conditions pointed out with the dobutamine stress, 3 patients were not treated surgically. With an aggressive intra- and perioperative monitoring 73 patients underwent a surgical treatment: they were 28 aorto-bifemoral, 3 aorto-aortic grafts, 1 aorto-bisiliac thoraco-abdominal interposition graft, and 20 aorto-bifemoral, 4 aorto-femoral, 1 aorto-aortic thoraco-abdominal, 1 aorto-renal by-pass and 7 aorto-iliac-femoral thromboendoarterectomies. In the postoperative period 4 cardiac ischemic complications and 2 deaths (2.5%) were observed. CONCLUSIONS: According to our personal opinion, stress echocardiography can be considered a test with a excellent feasibility and safety rate, not expensive and with a good reproducibility and reliability. It allowed to predict the cardiac risk in our patients suggesting not only the surgical but also the anesthesiologic and the perioperative therapeutic management.

Diagnosis, Differential↗

Arterial injury of the axilla: an unusual case after blunt trauma of the shoulder.

The lesion of an axillary artery after a shoulder dislocation without bone fractures is very rare. The most common lesion is the subtotal transection of the vessel. Vascular injuries may be associated with nervous lesions whose incidence ranges from 27 to 44%. The nervous lesions are highly invalidating. The symptoms which recur most frequently are motor and sensitive deficiencies and a distal ischemia which, in some cases, may not be noted owing to the extensive collateral network. Whenever these symptoms are covered or absent, as in this case report, an angiography of the upper limb becomes essential for correct diagnosis and treatment.

Accidental Falls↗

[Endovascular treatment of isolated aneurysms of the hypogastric artery: technical considerations apropos of 2 cases].

Isolated aneurysm of the internal iliac artery is uncommon, with an incidence approaching 0.4%; its diagnosis is difficult; its natural course is progressive expansion and rupture. Two cases of hypogastric aneurysms, promptly treated with embolization, are reported. In selected patients the endovascular technique can represent a good alternative to the traditional surgical treatment that is associated with higher complication and mortality rate.

Aged↗

[Dacron-EXS prosthesis in axillo-femoral bypass].

Twenty-eight axillary by-pass were performed in 27 patients using a dacron externally supported prosthesis. This group of patients has been compared with two other groups in which a dacron knitted (20 p.) or a PTFE (55 p.) prosthesis were implanted. A three years patency has been respectively: 66.6% (EXS), 57.7 (PTFE), 45.5 (Knitted Velour).

Aged↗

Telethermography and axillary node status as predictors of early relapse in breast cancer: preliminary report.

The authors report on 141 primary, non-metastatic, breast cancer patients with a minimum follow-up of 12 months after surgery to a maximum of 5 years. All cases were studied according to the patterns of the preoperative telethermography (TH) and nodal status (N). Prognosis was evaluated in terms of incidence of relapse. A statistically significant correlation was found between TH+ and early relapse, and for N+, but there was no correlation between TH and N, both for negative and positive values. The results suggest a complementary prognostic value of the two parameters.

Breast Neoplasms↗

Theoretical and practical aspects of receptor hormone assay in breast cancer.

The Authors have discussed the importance of ER/PR assay in breast cancer care. 162 patients were studied. The dextran-coated charcoal technique was used as the standard most readily available. The Authors point out the importance of specimen handling as is shown by time-decay studies, and the differences in ER/PR level at the time of the biopsy and mastectomy cut-section, and its eventual influence to better understanding assay results. The establishment of a center of control between different labs would also help in the development of more exact regimens for cancer care.

Breast Neoplasms↗

[Bilateral carcinoma of the breast].

In the light of literature and personal experience the Authors analyse the problem of bilateral breast cancer. Distinction between primary cancer (synchronous or metachronous) and metastasis in the second breast is made on the bases of clinical and histological criteria. Lobular cancer, either in situ of infiltrating, has a higher incidence of bilaterality. Aethiology, incidence, prognostic significance of the second cancer are briefly discussed; particularly, it is emphasized that there is a "high risk" group of patients in which the incidence of primary contralateral cancer is much higher. The Authors stress the importance of clinical examination of the other breast at the time of initial mastectomy for a proven breast cancer. The risk of metachronous cancer may be prevented by prophylactic contralateral mastectomy in the "high risk" patients or by random biopsy of the opposite breast in all the patients undergoing surgical therapy for cancer in the first breast. It is opinion of the Authors that early diagnosis may be also obtained if the patients are carefully followed by regular physical examinations and by diagnostic aids (mammography, ultrasonography, thermography).

Breast Neoplasms↗

[Testicular atrophy and gonadotropin activity in rats with portacaval anastomosis].

Rats subjected to porto-caval shunt present, even after a rather long period since the operation (5 months), a moderate atrophy of the testicles. This phenomenon occurs because of a reduced gonadotropic activity of the pituitary gland, consequent upon a more or less increased inhibition of the hypothalamic GTH-RF production. The abnormal depression of the hypothalamic activity is due to a scarce metabolism of the sexual hormones following the operation.

Animals↗

[Late obstructions of aorto-bifemoral prostheses].

The factors underlying late thrombosis of aortobifemoral by-pass are analysed on the basis of personal experience and reported data. They are considered to be due to progressive degradation of the prosthesic tissue and, particularly, to the lack of an adequate back flow route, apart from any faults in the actual construction of the femoral anastomosis. Treatment of the thrombotic complication involves considerable technical and operating problems which have two main solutions: substitution of the thrombosed branch, or its disobstruction. Intimately linked with restoral of by-pass patency is the reconstruction of an adequate back flow route either by means of profundaplasty or by extending the branch as far as popliteal level. Of 83 patients discharged with patent prosthesis, thrombosis occurred in 7 and 10 reoperations were necessary. Reconstruction of branch patency was done in the majority of cases by thrombectomy. Profundaplasty was associated in 4 cases while in other 4 popliteal extension was necessary. Analysis of results shows that the operation of choice on the affluxion route seems to be replacement of the thrombosed branch.

Aorta, Abdominal↗

Prevention of edema and flight microangiopathy with Venoruton (HR), (0-[beta-hydroxyethyl]-rutosides) in patients with varicose veins.

The aim of this open study was the evaluation of the effects of HR (Venoruton) at a dose of 1 g/day on the prevention and control of flight microangiopathy and edema in subjects with varicose veins and moderate chronic venous insufficiency flying for more than 11 hours. Patients with varicose veins, edema, but without initial skin alterations or complications, were included. Measurements of skin laser Doppler (LDF) resting flux (RF) venoarteriolar response (VAR), ankle swelling (RAS), and edema were made within 12 hours before and within 3 hours after the flights. The resulting edema after the flights was evaluated with a composite edema score (analogue scale line). A group of 20 subjects was treated with HR (1 g/day, starting 2 days before the flight and 1 g for every 12 hours on day of travel). Another group of 18 subjects formed the control group. The length of the flights was between 11 and 13 hours; all seats were in coach class. Fifty patients were enrolled and 38 patients were evaluable at the end of the trial. The 2 groups (treatment and control) were comparable for age and sex distribution. The decrease in RF was significant in both groups with a higher flux at the end of the flight in the HR group (p < 0.05). The venoarteriolar response was decreased at the end of the flights; the decrease was lower in the HR group (p < 0.05). The increase in RAS and the edema score were significantly lower in the HR group. In conclusion HR is useful for reducing the level of microangiopathy and the increased capillary filtration and in controlling edema in patients with venous disease in long flights. The higher level of flux and VAR and the reduction in edema indicate a positive effect of HR on the microcirculation. This study confirms that HR prophylaxis is effective to control flight microangiopathy associated with edema.

Aerospace Medicine↗