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Biomedical subjects

R Amin

Publications and source records attributed to R Amin.

At least 73 records · Page 4Linked to original sources
PubMed1985

Extramedullary plasmacytoma of the lung.

Three patients with extramedullary plasmacytoma of the lung are described, one of whom also had cervical lymph node metastasis, with the production of an M-protein. The production of M-protein normalized after successful treatment of the localized disease. In all three patients, the disease was locally controlled with radiation therapy, but it became generalized from 6 months to less than 3 years of the initial presentation.

Aged↗
PubMed1985

Fatal ruptured duodenal varix: a case report and review of literature.

The incidence of bleeding duodenal varices is exceedingly rare. We report a case of a 35-year-old chronic alcoholic who died of severe fatal upper gastrointestinal bleeding from a ruptured duodenal varix located in the second portion of duodenum. This diagnosis was suspected at endoscopy and was confirmed at autopsy. A review of literature shows 20 case reports of bleeding duodenal varices with two fatalities. While the duodenal bulb is the most common site of varices, the second portion of duodenum appears to be the next most common site. From all of the possible causes of duodenal varix, chronic liver diseases, mainly cirrhosis, remains the predominant etiological factor accounting for 30.7% of reported cases.

Adult↗
PubMed1984

Horner's syndrome with ipsilateral vocal cord and phrenic nerve palsies.

Two further cases of a recently described syndrome (Rowland Payne, 1981) constituting a triad of sympathetic ophthalmoplegia, phrenic nerve palsy and ipsilateral vagus or recurrent laryngeal nerve paralysis are described. This is a syndrome of signs, but hoarseness, dysphagia, dysaesthesia and pain in the ipsilateral shoulder may be associated symptoms. Development of this syndrome in patients with malignant disease does not necessarily signify a very grave prognosis.

Adult↗
PubMed1983

Hypertrophic osteoarthropathy without radiographic evidence of new bone formation.

A 70-year-old man with florid symptoms of hypertrophic osteoarthropathy for over a year presented without radiographic evidence of new bone formation. His symptoms improved after exploratory thoracotomy, but recurred with lesser severity a year later with tumour recurrence on the chest wall. Absence of new bone formation was again demonstrated radiologically as well as by isotope scan.

Adenocarcinoma↗
PubMed1983

Endobronchial involvement in Wegener's granulomatosis.

Right middle lobe collapse as a result of endobronchial involvement with Wegener's granulomatosis is reported in a 60-year-old woman. A review of the literature has revealed 6 cases of lobar collapse, only 2 of which had endobronchial disease.

Bronchial Diseases↗
PubMed1983

Effect of pregnancy and diabetes on myofibrillar protease activity in maternal and fetal muscles.

The activity of protease was investigated by cleavage of 14C-labelled globin by the isolated myofibrillar fraction of maternal and fetal muscles of nonpregnant, pregnant, and pregnant diabetic rats, on days 15 and 20 of pregnancy. Diabetes was produced by i.p. streptozotocin injection on day 5 or 12 of pregnancy. There was no change in muscle protease activity on day 15 of pregnancy in nondiabetic rats, compared to nonpregnant control rats, whereas on day 20 protease activity rose in the gastrocnemius by 25%, in the diaphragm by 30%, and only slightly in the heart. Diabetes, imposed during days 12-20 of pregnancy, induced a further increase in protease activity in the gastrocnemius (42%), diaphragm (47%), and heart (25%). In rats with diabetes lasting from day 5 to 20 of gestation there were only slight further increases in protease activity. In contrast, maternal diabetes did not induce changes in myofibrillar protease activity of fetal leg or heart muscles compared with the corresponding muscles of fetuses of nondiabetic rats. The increased protease activity on the maternal side occurred at low insulin levels and/or reduced insulin sensitivity, whereas the absence of changes in protease activity on the fetal side was associated with sustained or even increased presence of insulin. This suggests that the adaptive changes in protease activity, in both pregnancy and superimposed diabetes, are related to insulin availability and its effectiveness.

Adaptation, Physiological↗