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R Ansorg

Publications and source records attributed to R Ansorg.

94 records · Page 6Linked to original sources

Non-value of Aspergillus antigen detection in bronchoalveolar lavage fluids of patients undergoing bone marrow transplantation.

A commercially available antigen assay (Pastorex Aspergillus) was used to detect Aspergillus antigen in serial bronchoalveolar lavage (BAL) fluids and sera of patients undergoing bone marrow transplantation (six patients with autopsyproven aspergillosis and 10 control patients without evidence of fungal infection). Aspergillus antigen was not detected in 17 BAL fluids of the six patients with proven aspergillosis. In two of the six patients the assay gave positive results in serum specimens. Three of the 10 control patients showed reactive BAL fluids. It is concluded that the latex agglutination assay of BAL fluids has no value in the diagnosis of invasive (pulmonary) aspergillosis in patients undergoing bone marrow transplantation.

Adult↗

Comparison of the E test and a proportion dilution method for susceptibility testing of Mycobacterium kansasii.

The newly developed E test was compared with a conventional proportion dilution method for determining the sensitivity of Mycobacterium kansasii to amikacin, streptomycin, fusidic acid, rifampicin, clarithromycin, ciprofloxacin, ofloxacin, and fleroxacin. There was no more than one strain with different rating, except for ciprofloxacin. In this case, the breakpoint concentration had an unfavourable position at the top of the strip, and susceptible isolates in the dilution test were defined resistant in the E test. It is concluded that the E test is suitable for testing slowly growing mycobacteria other than tubercle bacilli, and may replace the more laborious dilution methods, particularly for testing M. kansasii.

Anti-Bacterial Agents↗

Activity of east African medicinal plants against Helicobacter pylori.

The activity of extracts from the East African medicinal plants Entada abyssinica (stem bark), Terminalia spinosa (young branches), Harrisonia abyssinica (roots), Ximenia caffra (roots), Azadirachta indica (leaves and stem bark) and Spilanthes mauritiana (roots and flowers) were evaluated against 12 strains of Helicobacter pylori. The most active extracts were those derived from T. spinosa with an MIC50 of 125 micrograms/ml, an MIC90 of 250 micrograms/ml and an MIC range of 62.5-500 micrograms/ml. An MIC50 of 250 micrograms/ml and an MIC90 of > 4,000 micrograms/ml was reached by H. abyssinica with a range of 125-->4,000 micrograms/ml and by X. caffra with a range of 62.5-->4,000 micrograms/ml, respectively. It is concluded that these plants contain compounds with antimicrobial activity against H. pylori.

Africa, Eastern↗