PubMed Health⌕ Search

Biomedical subjects

R Aschoff

Publications and source records attributed to R Aschoff.

6 recordsLinked to original sources
PubMed2006

[Extensive Fournier gangrene. A dermatologic emergency].

Fournier gangrene is a necrotizing fasciitis of the perineal and genital region, which almost exclusively affects men. The cause is a polymicrobial infection associated with superficial trauma, urological diseases and operations, as well as colorectal diseases. Diabetes mellitus, alcoholism, immunosuppression and other severe illnesses are frequent co-factors. Immediate administration of systemic broad-spectrum antibiotic therapy with coverage of both gram-positive and gram-negative bacteria combined with surgical debridement and intensive medical care can lower the high mortality rate of this condition.

Adult↗
PubMed2003

[Topical treatment of psoriasis: a systematic update].

Classical topical treatment regimens in psoriasis including dithranol and corticosteroids are widely used and have been supplemented in recent years by topical vitamin D preparations, by vitamin D analogues and topical retinoids. The combination of these preparations with each other, with UV light or with systemic drugs often lead to improved effectiveness and tolerability when compared with the respective monotherapy. In private offices, the combination of calcipotriol with various corticosteroids is very commonly prescribed for patients with mild to moderate psoriasis. This combination can be sequentially applied twice daily or--in a newly introduced fixed preparation--once daily. In severe psoriasis requiring systemic treatment a concomitant effective topical treatment regimen can greatly improve the overall longtime management in affected patients.

Administration, Topical↗
PubMed2003

[The treatment of keloids].

Keloids are benign fibrous growths with characteristic clinical features, whose underlying pathogenic mechanisms are not fully understood. While numerous treatment approaches are available, there is little evidence for efficacy based on controlled clinical studies. Therapeutic results are often not satisfactory. The best approach employs multiple modalities appropriate for the stage of the lesion. Combining invasive methods such as cryotherapy, surgery, intralesional steroid injections, laser or radiotherapy with external or physical approaches has helped to optimize treatment efficacy. Newer clinical studies with intralesional substances such as interferons which may directly influence collagen metabolism show promising results; these substances may be valuable therapeutic additions.

Adolescent↗