[Secondary prevention of opportunistic infections in HIV-infected patients].
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Biomedical subjects
Publications and source records attributed to R Asencio Marchante.
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Subacute thyroiditis is an inflammatory disorder of the thyroid caused probably by viruses. It is clinically characterized by the presence of anterior cervical pain and/or painful goiter, and rarely as fever of unknown origin or as prolonged fever syndrome. We report a case of a 49-year-old female admitted to the hospital because of fever during last month, leukocytosis and accelerated erythrocyte sedimentation rate. Following observation, slight tenderness over the thyroid gland and signs of hyperthyroidism occurred. After the laboratory studies, low thyroidal radioactive iodine uptake and fine-needle aspiration cytology (FNAC) of thyroid, she was diagnosed of subacute thyroiditis with hyperthyroidism. We believe that the etiologic agent was the Epstein-Barr virus because heterophile and Epstein-Barr virus-specific antibodies were positive. The patient was treated with acetaminophen (1.500 mg/day) with prompt and complete resolution of the clinical and laboratory abnormalities. There has been no recurrence of the disease during a 1 year follow-up.
This report concerns the clinical and bacteriological study of a female diabetic who presented with a febrile illness of sudden onset and acute toxemia. Physical examination at admission was unrewarding. A few hours after admission lesions characteristic of gas gangrene appeared in the right upper limb without prior trauma, and a clostridial infection was suspected. Bacteriological studies of the exudate and of the patient's blood led to the isolation of Clostridium septicum, thus confirming the clinical suspicion. The disease had a precipitous course and the patient died 12 hours after admission in spite of the administration of high doses of intravenous penicillin. While waiting for bacteriological data, early antibiotic treatment appears to be indicated in any diabetic patient with an acute toxic syndrome and absence of localized infection.
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