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Biomedical subjects

R Avery

Publications and source records attributed to R Avery.

8 recordsLinked to original sources

Feathered nest/gilded cage: parental income and leaving home in the transition to adulthood.

The growing study of leaving home in young adulthood in the United States has been hampered by data and measurement problems, which are producing a major theoretical confusion about the role of parental resources in influencing young adults' leaving home. Does high parental income retain young adults in the home or subsidize their leaving (and parental privacy)? This paper uses the 1984 panel of Survey of Income and Program Participation to clarify this issue, and shows that the effects of parental resources differ depending on the route out of the home under consideration (marriage or premarital residential independence). Effects change substantially over the nest-leaving ages, but relatively few differences are found between young men and young women.

Adolescent

Optic disc edema after bone marrow transplantation. Possible role of cyclosporine toxicity.

Bone marrow transplantation has become widely used in the treatment of aplastic anemia and leukemia. Cyclosporine is used as prophylaxis against graft-versus-host disease. The authors report on eight cases of optic disc edema in patients taking cyclosporine after allogenic bone marrow transplant. Thorough evaluation revealed a possible alternate cause in two cases. In all cases, the optic disc edema resolved after discontinuing or decreasing the cyclosporine. Although cyclosporine has not previously been associated with optic disc edema, it has been implicated as the cause of a variety of neurologic side effects. Bone marrow transplant patients taking cyclosporine should be followed for the development of optic disc edema.

Adolescent

Disability, residential mobility, and changes in living arrangements.

The extent of mobility and changes in living arrangements associated with disability were studied using data from the 1984-86 Longitudinal Study of Aging. It was hypothesized that persons with significant limitations in their ability to perform normal daily activities (ADLs and IADLs) in 1984 would be more likely to move, more likely to be living with others in 1986, and more likely to have entered an institution between 1984 and 1986 than those without limitations. When only those variables that were measured in 1984 were used as predictors, this turned out to be true for institutionalization and for living with others in 1986. However, among those remaining in households, residential mobility showed little relationship to disability when other variables were controlled. When the change in disability between 1984 and 1986 was added to the prediction equation, there were strong relationships between changes in disability and both residential mobility and adjustment in living arrangement, suggesting that people respond quickly to significant changes in disability. However, because we cannot be sure that the changes in disability preceded the mobility or changes in living arrangements, we cannot claim to have established a causal link between these events.

Activities of Daily Living

Posterior chamber IOL implantation with suboptimal posterior capsular support.

A posterior chamber intraocular lens (PC/IOL) was implanted in 24 patients with suboptimal posterior capsular support due to preoperative or intraoperative rupture of the posterior capsule or zonules in which at least six clock hours of peripheral zonular support remained. The PC/IOLs were implanted, with ciliary sulcus haptic placement, with special attention to sulcus fixation of the haptics over the zone of residual zonular support. All of the IOLs have remained centered after a mean follow-up 10.5 months. We conclude that a PC/IOL can be successfully implanted and its position maintained if at least six clock hours of peripheral zonules remain.

Adult

Pharmacotherapy of drug abusers: adjunctive psychopharmacologic management of nonopiate mixed substance abusers in an outpatient setting.

Conventional practice in treating nonopiate mixed substance abusers have avoided the use of pharmaceuticals because of the strong drug orientation of this patient population. The author's impressions are that this is a maladaptive treatment polarization, and that psychopharmacotherapy of this group of patients is not only sometimes useful but necessary for some individuals. Diagnostic syndromata and problems specific to this patient population are delineated along with our experience in pharmacotherapy.

Affective Symptoms

Electrical stimulation of the conus medullaris in the paraplegic. A 5-year review.

In 1970 we carried out the first electrode implantation of the conus medullaris of a 17-year-old male paraplegic to control the emptying of his paralyzed bladder. Our patient has used electromicturition for 6 years to successfully empty his bladder and prevent urinary infection. To date, a total of 11 paraplegic patients have been implanted (6 males, 5 females). The cause of the paraplegia was the result of trauma, and the implants were performed from 16 days to 15 years postinjury. All the patients had experienced numerous urinary infections and required constant catheter drainage, and it was the opinion of our urologic associate that current methods of control of the bladder problem were of no avail. The bladder was considered to be atonic in 7 patients and spastic in 4. The results indicate that after a follow-up of 1--6 years, 8 patients have complete control of voiding by electrical stimulation (4 female, 4 male). 2 of the males required partial sphincterotomy to improve emptying, but none of the females experienced sphincter interference. One male quadriparetic patient died 7 months postimplantation of pneumonia and hepatitis. There have been no infections related to the implantable device; however, 1 female broke the connecting wires to the spinal cord electrode during a paraplegic basketball game. In addition to the induced electrical contraction of the bladder, we have observed increased autonomic activity below the level of the spinal cord transection, improved defecation, reduction of spasticity in the paralyzed legs, penile erection in males, and reduction of decalcification of the long bones. This group of patients represents the longest use of an implantable electronic device to control bladder function.

Adolescent