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Biomedical subjects

R Avisar

Publications and source records attributed to R Avisar.

At least 37 records · Page 2Linked to original sources

[Epiphora as an expression of dry eye].

One of the most common ophthalmic disorders in the elderly is epiphora, a watery eye with overflow of tears. In some patients it appears in a paradoxical form: dry eye indoors and tearing outdoors. We present a 76-year-old man and a 58-year-old woman with this disorder. Despite diagnosis of dry eye, confirmed by several tests, they complained of epiphora. This ceased after treatment with tear substitutes, bromhexine and occlusion of the lacrimal puncti. The possibility that tearing may be an expression of the dry eye state should always be considered.

Aged↗

"Cold" corneal abscess in psoriasis: a case report.

A single case of "cold: corneal abscess in a psoriatic patient was considered worth reporting as there are no other cases described in the literature. The importance of the correct diagnosis and the management are discussed.

Abscess↗

Clinical trial of bromhexine in Sjögren's syndrome.

Tear secretion and lysozyme tear content were measured in 30 patients with Sjögren's syndrome after treatment with oral bromhexine, 32 mg/day. In 21 patients (70%) there was a marked increase in tear secretion and in lysozyme content. In patients with keratoconjunctivitis sicca (KCS) good results in clarifying the mucoid eye discharge were obtained. A remarkable amelioration of xerostomia was also noted. Six other patients, serving as controls, were given a placebo and bromhexine. The placebo had no influence on the rate of tear secretion, while bromhexine caused it to increase in 70% of the controls. This side effects of bromhexine treatment encountered in the present study were negligible and transient. We consider bromhexine to be the drug of choice in the treatment of Sjögren's syndrome.

Bromhexine↗

Lysozyme content of tears in patients with Sjögren's syndrome and rheumatoid arthritis.

In 37 patients and 143 control patients we estimated tear fluid lysozyme content by the Micrococcus lysodeikticus agar diffusion assay. We found no correlation between the titer of lysozyme in tear fluid and the rate of tear flow. Decrease in lysozyme production was found to be a sensitive indicator of the involvement of the lacrimal system in Sjögren's syndrome.

Adult↗

Tear secretion in patients with nonspecific eye complaints.

Tear secretion, as measured by Schirmer's test, was significantly reduced in 42 (9%) of 466 patients with nonspecific anterior segment complaints. One of these 42 patients were found to have systemic lupus erythematosus and another had benign mucous membrane pemphigoid.

Adult↗