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Biomedical subjects

R Ayerbe García

Publications and source records attributed to R Ayerbe García.

7 recordsLinked to original sources
PubMed2002

[A man with lung cancer and tuberculosis: a false positive by positron emission tomography and its clinical repercussions].

Positron emission tomography (PET) has come to play an increasingly important role in the evaluation of lung cancer patients, both for diagnostic staging and post-treatment follow-up. As is true for other techniques, PET gives false positive and negative results. False positives have been described in the presence of certain active infections and inflammatory lesions, such as tuberculous granulomas, coccidioidomycosis, aspergillosis and histoplasmosis. We report the case of a man whose PET gave a false positive and in whom both lung cancer and tuberculosis were present. A radical change in therapeutic approach was required, making the case interesting.

Antitubercular Agents↗
PubMed2001

[Adaptation parameters in non-invasive mechanical ventilation. Experimental comparative study].

OBJECTIVE: To evaluate response to pressure and flow triggering in an experimental model of the normal, obstructive and restrictive lung with six non-invasive mechanical ventilation units: Vintil+ (VP), Respironics STD20 (RR), Puritan Bennet 335 (PB), Quantum (QT), DP90 (DP) and Sullivan II ST (SV). METHOD: Analog signals of volume, pressure and flow from a lung simulator were recorded by a Mingograph 34 polygraph. Positive inspiratory pressure (PIP) was 12 cmH2O, respiratory rate was 17 cycles/min, end expiratory pressure (PEEP) was 4 cmH2O, and inspiratory effort (P0.1) was 4 cmH2O. Parameters calculated were negative trigger pressure, trigger time (or the flow wave delay in triggering), and the percentage of peak inspiratory flow at which a change to exhalation or cycle phase. RESULTS: The RR and PB units had the best trigger response with pressure triggering below -1 cmH2O and trigger times less than 100 ms. VP proved to have the poorest response. The cycle of the RR agreed most closely with the standard (5-25% of peak inspiratory flow), whereas change to exhalation occurred with the other units with zero flow (in all patterns with DP90, and in restrictive patterns with PB and VP) or greater than 50% of peak inspiratory flow (in all models with QT). Analysis of pressure curves showed great differences in slope, plateau and depressurization. CONCLUSIONS: The RR unit proved to have the most homogeneous behavior for all the phase parameters studied as being the ones that most influence a patient's adaptation to a ventilator.

Models, Anatomic↗
PubMed1997

[Relation between asthma and atopy markers in children and young adults].

The aim of this study was to assess whether atopy, measured as total IgE level (IgEt) and/or skin test (ST) reactivity is related to bronchial asthma in the same way in children and young adults. Three hundred fifty-three children between 11 and 15 years of age (mean 12.6 years) and 208 adults between 20 and 44 years old (mean 32.1 years) were selected randomly as representative of persons living in the city of Huelva (Spain). All subjects filled out a questionnaire on respiratory symptoms (The European Community Respiratory Health Survey--[ECRHS]) and were given a methacholine challenge test (MT) with results expressed as PD20 as well as IgEt and ST assessments of atopy. We defined bronchial asthma as the association of having experienced wheezing within the last 12 months and having a positive ST. Among children, 4.5% suffered bronchial asthma. Among adults the proportion was 5.3%. The IgEt value that best discriminated between asthmatics and non asthmatics was 145.5 U/ml in children (sensitivity 75% and specificity 69.1%) and 96.6 U/ml in adults (sensitivity 90.9% and specificity 73.6%). A logarithmic transformation (log IgEt) was used to study the relation between bronchial asthma and IgEt. By simple analysis, IgEt and ST were related to bronchial asthma in children (p = 0.002 and p < 0.0001, respectively), while only IgEt (p < 0.001) was related in adults. By multiple regression analysis, controlling for both factors simultaneously as well as for smoking in adults, we found that ST (p = 0.023) but not IgEt was related in children, whereas IgEt (p = 0.0005) but not ST was related in adults. We conclude that the two markers of atopy studied are related to bronchial asthma differently and have different manifestations at different stages of life. ST is more useful in children, whereas IgE determination is of more use in adults.

Adolescent↗
PubMed1992

[Short-term effects of respiration with external negative ventilation --shield-type respirator-- on the pulmonary function in COPD].

With the objective to test the effect of intermittent and short term rest in respiratory muscles in patients with COPD and maintained hypercapnia we have studied 34 patients in a stable condition: 23 were part of the study group (Group I) and 11 were the control group (Group II). After a complete functional basal study, patients in Group I were treated with intermittent rest of their respiratory muscles, through a negative pressure external respirator--shield type--during three consecutive days. We got, in this study group, a significative improvement in the maximum inspiratory pressure measured at residual volume (PI max RV), which went from 66.6 +/- 15.9 to 71.2 +/- 15.2 (p < 0.005), as well as a lowering, also significative, of partial pressure of CO2 in arterial blood (PaCO2) and in expired air (EFCO2), which went from 55.2 +/- 7.2 to 52.3 +/- 3 (p < 0.0002) and 3.3 +/- 0.5 to 3.1 +/- 0.5 (p < 0.01), respectively. Maximum inspiratory pressure measured to functional residual capacity (PI max FRC) experienced an increase in the limit of statistical signification. Rest of the parameters did not significantly change. These results back the hypothesis that in stabilized COPD with CO2 retention, a chronic fatigue of respiratory muscles could exist, and that intermittent rest of these muscles could mean an hypercapnia diminution, due to the improvement in the function of respiratory muscles.

Adult↗
PubMed1992

[Primary pulmonary leiomyoma. Presentation of 3 cases].

Pulmonary leiomyoma is a benign tumor of mesodermal origin, very rare of which only three cases have been described on the Spanish scientific literature. We present our experience with three new cases and discuss the clinical and therapeutic characteristics of these neoplasms according to their topographical localization. We insist on the need of a gynecological revision when females are affected, because its possible association with uterine tumors.

Adult↗
PubMedDate not supplied

[Usefulness of dehumidifiers in the reduction of acari concentrations].

This study analyzes the role of dehumidifiers in asthma prophylaxis. The efficacy of dehumidifiers in the reduction of Dermatophagoides in the bedrooms of 9 patients with specific allergies was evaluated, along with success in reducing in high concentrations of mite allergens (D. pteronissinus I). Results were compared with those for a control group of 8 patients with the same allergy. In the group in whose homes a dehumidifier was installed, there was a significant reduction in relative humidity in the bedroom (54.84 +/- 4.33% and 45.23 +/- 4.92%; p < 0.05) as well as a significant decreased in concentrations of D. pteronissinus I (2.313 +/- 1.831 to 0.42 +/- 0.44 microgram/g; p < 0.05). This was not the case of patients in the control group (51.15 +/- 7.38% to 60.5 +/- 6.15%; p < 0.05 and 3.28 micrograms/g +/- 4.46 to 4.24 +/- 5.10; p = NS).

Adolescent↗