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Biomedical subjects

R B Cady

Publications and source records attributed to R B Cady.

11 recordsLinked to original sources
PubMed1999

Physeal response to absorbable polydioxanone bone pins in growing rabbits.

Absorbable fixation materials would seem especially useful for treating transphyseal fractures in growing children, but their degradation products may affect physeal growth. The histologic response of an open physis to placement of transphyseal, polydioxanone (PDS), bioabsorbable pins was studied in skeletally immature New Zealand White rabbits. A 1.3-mm PDS pin was inserted across the right femoral physis, and a 1.3-mm empty drill hole across the left femoral physis served as a control. The animals were sacrificed at 3, 6, 9, and 12 weeks postsurgery. Biplanar radiographs, bone length measurements, and histology sections of the physis and adjacent bone were made. Three independent observers graded the histologic response of the physis to the drilling and implant. There was no evidence of inflammation, foreign body reaction, or distortion of the growth plate during the entire growth period. This suggests bioabsorbable pins do not cause any appreciable inflammatory response or adverse effect on physeal function during active longitudinal growth of the bone.

Animals↗
PubMed1992

The effects of fat interposition for central-physeal defects. A histologic study in rabbits.

The effects of autogeneic fat interposition in a central cylindrical physeal defect were observed in rabbits. A 3.6-mm longitudinal drill hole was made across the physis of the distal femur, bilaterally, in four- to six-week-old New Zealand rabbits. One side was filled with an autogeneic fat graft and the contralateral defect was left as a control. The rabbits were killed at intervals during the remaining growth period, and the defects were examined histologically. Although fat grafts reduced the rate of osseous bridging across the physis and allowed more longitudinal growth than controls, transverse regeneration of the physis did not occur in the eight-week period preceding closure. The lack of physeal regeneration across the gap may reflect an important difference between central and peripheral defects.

Adipose Tissue↗
PubMed1988

Ultrasonography for urinary tract evaluation in patients with congenital spine anomalies.

Outpatient pediatric orthopedic records were reviewed retrospectively in an attempt to identify all patients with congenital spine and urinary tract anomalies. All patients with a positive intravenous pyelogram (IVP) were asked to return for ultrasonographic evaluation. Urinary tract abnormalities were identified in seven (26%) of the 27 patients with documented IVPs. An additional patient was later added to the series, making a total of seven patients who returned for an ultrasonogram, which was then compared with the IVP. Observations and a review of the literature suggest that ultrasonography combined with urinalysis and serum creatinine is the screening protocol of choice in this patient population.

Humans↗
PubMed1987

Soft tissue anomalies in a patient with congenital tibial aplasia and talo-calcaneal synchrondrosis.

We have carried out the third in a series of anatomical dissections of amputated congenitally deformed human limbs in an attempt to determine the etiological relationship between the bony and soft tissue anomalies. This specimen consisted of a limb with congenital tibial aplasia and an adducted foot with five toes. The arterial and nerve patterns were reminiscent of those seen previously by us. The arteries were characterized by absence of the anterior tibial artery and an incomplete plantar arch. The superficial peroneal nerve terminated at the ankle. Extra branches from the sural, deep peroneal, and medial plantar nerves supplied branches to the dorsum of the foot. There were two extra muscles in the leg. The remaining muscles were normal, with the exception that most muscles normally inserting on the plantar surface of the foot inserted instead into a common tendon sheet. The tibia was replaced by a tendinous band, and the talus and calcaneus were united by a complete synchondrosis. The contralateral limb clinically appeared to have a clubfoot. The combination of an absent anterior tibial artery and an incomplete plantar arch is consistent with our theory that a reduced number of vessels puts the embryonic limb at increased risk of congenital defects due to the reduction in the number of collateral blood routes. Some event, such as extravasation of blood or embolization, may concurrently or subsequently compromise blood flow in the remaining vessels. We have previously observed abnormal arterial patterns similar to that described above in limbs having absence of the tibia and in other patients having clubfeet. The presence of abnormal arterial patterns in a limb with absence of the tibia and a contralateral limb with clubfoot suggests that absent tibia and clubfoot may be etiologically related.

Amputation, Surgical↗
PubMed1987

Posterior dislocation of the hip associated with separation of the capital epiphysis. A case report.

A 14-year-old boy with a posterior dislocation of the femoral head suffered an epiphyseal separation with reduction of the femoral neck into the acetabulum during an attempted closed reduction. He was treated by an open reduction with care taken not to damage the retinacular blood supply to the head. He did not develop avascular necrosis and is totally asymptomatic four years following his injury.

Adolescent↗
PubMed1984

Dosimetry of computerized tomography in the evaluation of hip dysplasia.

The usefulness of computerized tomography (CT) in the assessment of hip dysplasia has recently been given attention in the literature and concern regarding radiation dose has been raised. This study was undertaken to measure the radiation dose, both in and out of plaster, for plain films, arthrography, tomography, and CT. A method is suggested to reduce dosage by 80% without compromising diagnostic information. Our experience with 25 scans of patients aged 4 months to 39 years is presented.

Acetabulum↗
PubMed1984

Incidence, natural history, and treatment of scoliosis in Friedreich's ataxia.

We carried out a retrospective study of 42 patients with documented Friedreich's ataxia to answer four questions: what is the incidence and natural history of scoliosis in Friedreich's ataxia, and what are the results of operative and nonoperative treatment? We concluded that the incidence of scoliosis in true Friedreich's ataxia is extremely high. The curves tend to progress with the severity of the disease and often tend to progress after skeletal maturity. Bracing and electrospinal instrumentation have no role in treatment. Patients with progressive curves should have early surgical stabilization.

Adolescent↗
PubMed1983

Endocrinologic and metabolic factors in atypical presentations of slipped capital femoral epiphysis. Report of four cases and review of the literature.

Although the usual etiology of slipped capital femoral epiphysis (SCFE) is idiopathic, there are many underlying endocrinologic, biomechanical, metabolic, and connective tissue abnormalities that increase the predisposition to slippage. Four case reports and a review of the literature demonstrate tht hypopituitarism, renal rickets, radiation therapy, hypoestrogenic states, and chemotherapy can be associated with SCFE. Awareness of the variety of conditions under which SCFE can occur is an important factor in providing early diagnosis, since many patients undergo slippage at atypical ages. In metabolically and endocrinologically abnormal patients, surgical stabilization may need to be augmented by autologous bone grafting to ensure successful epiphyseodesis.

Adult↗
PubMed1981

"Cold" bone scans in acute osteomyelitis.

The diagnosis of acute osteomyelitis is often very difficult during the first 24 to 48 hours. Bone scanning has been a useful adjunct in this diagnosis by demonstrating increased uptake in the area or areas of involvement. Occasionally the pathological area is "cold" on scanning, which may lead to a misdiagnosis. This paper presents three cases demonstrating this unusual finding.

Acute Disease↗