A complication of retrograde endotracheal intubation.
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Biomedical subjects
Publications and source records attributed to R B Contrucci.
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Epithelial-myoepithelial carcinomas are a rare form of salivary gland carcinoma. They are found predominantly in the parotid glands and rarely occur in the upper airway and in minor salivary glands. These neoplasms are found predominantly in women in the seventh and eighth decades of life and account for less than 1% of all salivary gland ductal carcinomas. These tumors may demonstrate infiltrative and destructive patterns, with a tendency to metastasize. It is recommended that they be approached and treated along the same avenues as any other malignant lesions of the head and neck.
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Each of 16 Bolivian-phenotype squirrel monkeys of mixed sex had a machine bolt mounted on the skull with acrylic cement; 13 were provided with temporary plaster body casts allowing free movement. With eyes open, all were rotated in the horizontal plane at 30 rpm every other day until vomiting occurred or for a maximum duration of 120 min/spin. Latencies for motion-sickness signs were recorded under three experimental conditions: free movement, torso fixed to an aluminum frame and both torso and head restrained by bolting to the frame. Subsequently, 10 monkeys from this sample were rotated while blindfolded with head and torso immobilized. Results partially confirmed human and animal findings reported by others: reduced mobility was accompanied by a reduction in the incidence and an increase in the latency of motion sickness. The importance of optokinetic input for the generation of motion sickness in this species was clear.
Under a variety of experimental conditions, nonrestrained adult male squirrel monkeys were subjected to continuous rotation in the horizontal plane at 33 rpm. Severity of motion-induced sickness was quantified by measuring latencies of three responses associated with sickness. Per- and postrotational nystagmus was recorded from a subsample of monkeys with permanent recording electrodes implanted in the bony orbits. Incidence of sickness depended on the time limits of stimulation imposed, and it occurred in a maximum of about 90 per cent of test sessions if rotation was continued for two hours. When subjected to ten once-per-day rotation sessions, only a few monkeys showed evidence of developing transient habituation of onset of motion sickness. Mean frequency of emetic episodes, however, declined over the latter half of the rotation series. Restricting visual cues by blindfolding the monkeys prevented most subjects from vomiting.
The current status and implications of the neurohumoral hypothesis of motion-induced vomiting are reviewed. Data show that squirrel monkey subjects vomit only once if horizontal rotation is terminated immediately on the occurrence of the emetic response. Refractory periods for multiple vomiting episodes concurrent with continued rotation are sufficiently brief to suggest that the expected presence of the hypothetical neurochemical agent in the cerebrospinal fluid of the fourth ventricle should continue to evoke more than one vomiting response even after cessation of motion stimulation. In its present form, the hypothesis is conceptually vague and should be developed further to account for a mechanism by which the expected recurrent emesis is inhibited during the period when the alleged agent is a potentially effective stimulant.