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Biomedical subjects

R B Glass

Publications and source records attributed to R B Glass.

32 records · Page 2Linked to original sources

Gallium scintigraphy in American Burkitt lymphoma: accurate assessment of tumor load and prognosis.

The radiographic evaluation of 18 children with American Burkitt lymphoma was analyzed retrospectively. Pretreatment gallium-67 (67Ga) scintigraphy, done in 12 children, was interpreted as normal in only three children. In the other nine children, 67Ga scans demonstrated more sites of tumor involvement than any other method. Pretreatment abdominal computed tomography and sonography were valuable for evaluating ascites, density and size of the liver and spleen, renal involvement, and the presence of lymphomatous soft-tissue masses. Sonography was less accurate at localizing tumor deposits, but more sensitive to small amounts of ascites. Any of these methods is an effective way of following response to chemotherapy. However, it appears that sequential 67Ga scintigraphy may have significant prognostic value, as those children whose scintigrams reverted to normal within 6 months have survived.

Adolescent↗

Atypical findings on computed tomography in tuberous sclerosis. Case reports.

In 3 patients with tuberous sclerosis computed tomography showed numerous low-density areas suggestive of brain demyelination. In addition, solitary small subependymal calcifications were noted. These features in an infant or child with unexplained seizures should alert one to the diagnosis of tuberous sclerosis.

Cerebral Cortex↗

Computed tomographic appearance of laryngoceles.

The diagnosis of laryngoceles is usually not difficult and can be made clinically and by conventional radiological methods. Computed tomography is a useful, non-invasive, complementary method for confirming the diagnosis especially in complicated cases.

Dilatation, Pathologic↗

Computed tomographic diagnosis of basilar artery ectasia.

Basilar artery ectasia (BAE) can cause numerous neurological signs and symptoms, and awareness of its existence can obviate the need for vertebral angiography. The appearance of BAE on computed tomography is almost pathognomonic, and recognition thereof is important in order to prevent the mistaken diagnosis of a pontine or cerebellopontine angle tumour.

Basilar Artery↗

Computed tomographic findings in primary mandibular osteosarcoma.

Osteosarcoma of the mandible is a rare tumour. Two cases examined by computed tomography (CT) are presented. The osteolytic, osteoblastic and extra-osseous components are excellently shown by CT. The attenuation coefficient of calcified and non-calcified osteoid is extremely variable, with densities ranging from +19 to +320 EMI units. The extension of lesions into the pterygopalatine fossa, infratemporal fossa and cranial cavity are precisely defined on CT, information which is necessary for surgical and radiotherapy planning.

Adolescent↗

Sacrococcygeal chordoma in young adults.

Sacrococcygeal chordoma in young adults is rare. Two patients, aged 29 and 34 years, are presented. Computed tomography plays an important role in delineating the extent of bony destruction and soft-tissue involvement. This information is necessary for treatment which may include surgery, radiotherapy and/or chemotherapy. A review of sacrococcygeal chordomas is presented.

Adult↗

Unilateral cerebellar hypoplasia.

A case of unilateral cerebellar hypoplasia is presented. This was an incidental finding in a patient with no evidence of neuromuscular or metabolic disease and no past history of trauma, anoxia, or perinatal difficulties. Computed tomographic scans showed posterior fossa asymmetry with underlying unilateral cerebellar hemisphere hypoplasia. In addition, there was overlying skull table thickening and excess petrous pneumatization on the affected side.

Cerebellum↗

MR imaging of osteoid osteoma.

An osteoid osteoma was detected in a young boy with a classic history for this lesion. Plain radiography was not helpful but ultrasound and magnetic resonance imaging demonstrated the tumor nidus.

Child↗

Lumbar compression fractures secondary to lap-belt use in children.

The correlation between flexion-distraction injuries and lap-belt use has been well documented. Over a 10-year period, we identified seven children admitted to Children's National Medical Center, Washington, DC, with compression fractures of the lumbar spine secondary to lap-belt use. Four were rear seat passengers, and three were in the front seat. The average age was 7 years. Four of the seven (57%) suffered associated abdominal injuries. One died of an associated head injury. We hypothesize that the mechanism of injury in these cases was similar to that in flexion-distraction injuries. The increased elasticity in the posterior ligamentous complex in children may be responsible for the occurrence of these compression fractures rather than the expected flexion-distraction-type injuries.

Abdominal Injuries↗