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Biomedical subjects

R B Griffiths

Publications and source records attributed to R B Griffiths.

11 recordsLinked to original sources

Intersectoral collaboration in animal and human health.

A review is made of the health fields where collaboration between veterinarians and physicians and with other professions is most needed. The main obstacles encountered in this collaboration are recognized in institutional and attitudinal factors such as the type of administration in which veterinary services are located, economic interests, isolated spheres of activity of both veterinarians and physicians, reactions of the public to Veterinary Public Health action, insufficient fund allocation, etc. Control of echinococcosis/hydatidosis and brucellosis is given as an example of fruitful intersectoral collaboration supported by health institutions at local and international levels. It is stressed that the need for intersectoral collaboration is being increasingly and universally accepted with the active involvement of concerned organizations at all levels.

Animals↗

Speed of injection and spread of bupivacaine in the epidural space.

Speed of injection of bupivacaine was assessed in 73 women who received epidural analgesia in labour. Rapid injection was shown to produce quicker onset of epidural block and more reliable perineal anaesthesia than slow injection, but there was no difference in the final extent of the block.

Anesthesia, Epidural↗

Atracurium infusions in patients with renal failure on an ITU.

An infusion of atracurium was used (after an initial bolus dose) in five patients with renal and respiratory failure, who were being subjected to intermittent positive pressure ventilation before renal dialysis. Neuromuscular function was monitored by the train-of-four pattern of stimulation. In three patients, atracurium 0.6-0.7 mg/kg/hour completely abolished the twitch response; in the other two (both of whom were markedly oedematous) this did not occur, even with a dose of 1.0 mg/kg/hour, although satisfactory clinical control was obtained. In all patients, there was rapid spontaneous recovery when the infusion was stopped. One patient convulsed, but plasma laudanosine levels taken at this time were below the toxic range. Atracurium infusions appear to provide easily controllable neuromuscular blockade in the intensive therapy unit, although these preliminary results suggest that larger doses may be required in the oedematous patient.

Acute Kidney Injury↗