PubMed Health⌕ Search

Biomedical subjects

R B James

Publications and source records attributed to R B James.

At least 19 recordsLinked to original sources
PubMed1981

Prospective study of mandibular fractures.

A one-year prospective study of mandibular fractures that included 253 consecutive patients with 422 mandibular fractures was completed at Charity Hospital, New Orleans. Nine major categories were studied. Patients with multiple mandibular fractures seemed to have a fracture pattern. Complications associated with mandibular fractures are influenced more by location of the fracture or fractures and the cause than by a few days' delay in treatment, the specific technique in treatment, or extraction of teeth associated with the fracture. Thorough knowledge of occlusion and the masticatory apparatus is paramount in successful treatment.

Adolescent↗
PubMed1980

Use of pocket inlay grafts and tuberoplasty in maxillary prosthetic construction.

A method of surgical and prosthetic rehabilitation of the severely atrophic maxillae using pocket inlay grafts and tuberoplasty is presented. At 2 1/2 years postoperatively, the denture in a patient treated in this manner remains stable with good retention and function. The principles presented may be applied in a variety of situations to achieve greater retention and stability of the maxillary denture.

Denture Design↗
PubMed1980

Wiskott-Aldrich syndrome: review of literature and report of case.

Wiskott-Aldrich syndrome has been described. Other reports and studies of the syndrome have been compiled. Discussion of the incompletely understood pathogenesis and current treatment modalities are included with a differential diagnosis of related conditions. Although this syndrome is uncommon, it is not rare. The patient's susceptibility to infection and propensity to bleed makes early recognition and vigorous treatment an important and challenging task. It is hoped that this report will foster awareness of such patients and the complications involved in treatment.

Diagnosis, Differential↗
PubMed1979

Synthesis and antibacterial activity of 1-hydroxy-1-methyl-1,3-dihydrofuro[3,4-b]quinoxaline 4,9-dioxide and related compounds.

A Free-Wilson analysis of the antibacterial activity found in a variety of quinoxaline 1,4-dioxides prepared and tested in these laboratories unexpectedly predicted that potent activity should be found in the case where the heterocyclic ring system was substituted with an acetyl group in the 2 position and a hydroxymethyl group in the 3 position (2). The synthesis and antibacterial activity of this compound, which was actually isolated in the hemiketal form (3), and of several of its derivatives are reported. 1-Hydroxy-1-methyl-1,3-dihydrofuro[3,4-b]quinoxaline 4,9-dioxide (3) possesses exceptional activity in vivo against Escherichia coli, Salmonella choleraesuis, and Pasteurella multocida.

Animals↗
PubMed1979

Surgical correction of infraorbital-maxillary deficiency.

Patients who have a maxilla that is retruded or hypoplastic, or both, but who have a mandible of normal position and size, will have degrees of flatness in the middle third of the face. Using systematic clinical evaluation and cephalometric skeletal analysis, a clinically recognizable facial deformity manifested by retrusion or hypoplasia, or both, of the maxilla, anterior zygoma, and infraorbital rims has been recognized. This deformity has been classified as infraorbital maxillary deficiency. The purpose of this paper is to describe an infraorbital-maxillary osteotomy for correction of this dentofacial deformity and to give a rationale for its use. The design of this osteotomy is determined by the skeletal deformity and can be classified as either low or high. The objective is to produce simultaneously a functional occlusion and facial harmony. Two of eight cases corrected by this surgical treatment are described.

Adult↗
PubMed1979

Microbiologic and antibiotic aspects of infections in the oral and maxillofacial region.

An overview of infection as it applies to the oral and maxillofacial region has been provided. The following conclusions are drawn: odontogenic infections are caused by microbes found in the host's oral flora; cultures of purulent material generally will yield three to six anaerobes and one aerobe, (the aerobe is usually a Streptococcus species); Gram stains of purulent material can aid in therapeutic strategies; anaerobic as well as aerobic cultures are necessary to isolate all pathogens; pathogens found in infections of bite wounds reflect the oral flora of the aggressor; early postoperative wound infections are caused by the host's own flora, whereas later infections may be caused by hospital-acquired bacteria; and hepatitis B and herpes simplex virus are occupational hazards. Recommendations have been made for antimicrobial prophylaxis and for treatment. We recognize that some of these selections may be controversial. For instance, the value of prophylactic antibiotics in orthognathic surgery is not well defined; recommendations were made only in certain instances. However, in severe penetrating maxillofacial injuries with devitalized tissue, recommendations for antibiotics were for broad and prolonged coverage. In this instance, use of antibiotics is considered therapeutic and not prophylactic. In each instance, we tried to validate the selection. Our rationale has been to choose the antibiotics most active against the likely pathogens; additionally, consideration was given to drug toxicity and adverse reactions. We regard penicillin as the preferred agent for prophylaxis and treatment of most odontogenic infections. Alternative drugs include cephalosporins, doxycycline, and clindamycin. Erythoromycin and tetracycline are considered less effective than the former agents. Finally, we believe that successful treatment of infection depends as much on changing the microenvironment of the infected tissue by debridement and drainage as on appropriate antimicrobial therapy.

Actinomycosis↗
PubMed1978

Cephalometrics for orthognathic surgery.

A cephalometric analysis especially designed for the patient who requires maxillofacial surgery was developed to use landmarks and measurements that can be altered by common surgical procedures. Because measurements are primarily linear, they may be readily applied to prediction overlays and study cast mountings and may serve as a basis for the evaluation of posttreatment stability.

Adult↗
PubMed1978

The surgical sequence of combined total maxillary and mandibular osteotomies.

In many instances, orthognathic surgical cases require multiple osteotomies in the maxilla and mandible to achieve the most desirable result. When the entire maxilla and mandible are freed from their relationship with the remaining craniofacial complex, accurate repositioning and adequate stabilization can present problems. These problems can be minimized by operating in the proper sequence or by staging the procedure. Staging should be considered for the more complicated cases; in any instance, the maxilla should be operated on first.

Adult↗
PubMed1976

Radionuclide bone imaging in the surgical treatment planning of odontogenic keratocysts.

Locally aggressive benign lesions of the jaws, such as odontogenic keratocysts and ameloblastomas, require complete excision in view of the high incidence of recurrence after incomplete surgical removal. Because of the limitations of conventional radiology as the sole technique for determining the extent of these lesions, the use of 99m-technetium-labeled bone-imaging agents is suggested. This method of defining the location of surgical margins is based on the agent's sensitivity as an indicator of subtle changes in bone metabolism. A case of an unusually large recurrent odontogenic keratocyst is presented in which the planning of the surgical procedure was predicated on the results of a bone scan of the jaws in addition to conventional radiology. This diagnostic procedure, especially when used in conjunction with conventional radiology, appears to be of considerable value in defining the extent of a variety of oral-maxillofacial bony lesions.

Female↗
PubMed1975

Postauricular approach for surgery of the temporomandibular articulation.

The adaptation of a postauricular approach for surgical exposure of the temporomandibular articulation is presented. The ease, safety, and predictability of extensive exposure have led us to use this approach exclusively for surgical intervention in this region. It has been effectively used in cases of trauma, pathologic conditions, and reconstruction involving the TMJ. In addition to the cases reported in this series, the procedure may be adapted to oblique subcondylar oestotomies and to the treatment of a variety of regional neoplastic processes and other forms of TMJ dysfunctions that may be encountered.

Humans↗