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Biomedical subjects

R B Lamb

Publications and source records attributed to R B Lamb.

3 recordsLinked to original sources

Pyomyositis of the anterior tibial compartment.

Five oncology patients developed bacterial pyomyositis involving the anterior tibial compartment and resulting in compartment syndrome with ischemia and abnormalities of neuromuscular function. All patients were neutropenic and thrombocytopenic, and four were receiving or had recently received cancer chemotherapy. Three infections were due to gram-negative bacilli and two to Staphylococcus aureus. Appropriate antimicrobial therapy and surgical drainage in four patients resulted in the resolution of these infections with good residual muscle function. To our knowledge, primary pyomyositis has never previously been known to cause compartment syndrome.

Adult↗

Concentration of 99mTc-HIDA and iopanoic glucuronide by the gallbladder.

To determine the ability of the gallbladder to concentrate Technetium 99mHIDA, both HIDA and iopanoic glucuronide were introduced directly into ligated gallbladders of anesthetized dogs. Serial bile samples were drawn to measure the concentration of each agent over a three hour period. Both biliary imaging agents were concentrated by the normal gallbladder. The results suggest that 99mTc-HIDA may be useful to study the gallbladder mucosal function of concentrating capacity in patients at risk for kidney damage by the standard cholecystographic agents like iopanoic acid.

Animals↗