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Biomedical subjects

R Bähr

Publications and source records attributed to R Bähr.

At least 19 recordsLinked to original sources

[The Askin tumor].

The Askin tumor, a primitive malignant small-cell tumor of the chest wall, is mostly seen among children and adolescents. It is closely related to Ewing's sarcoma of the same location, both tumors showing a chromosomal translocation t(11;22). Its origin from neuroectodermal cells is deducted from several ultrastructural details and from the expression of specific markers like NSE. Pain and deformation of the chest wall are the cardinal clinical signs of the tumor. Chest X-rays will frequently show destruction of ribs and pleural effusions. Effective therapy consists of radical surgery, local radiation and adjuvant chemotherapy. This multimodal concept allows minority of patients to remain disease-free but the overall outcome is rather unfortunate.

Adult

[Argon gas embolism in laparoscopic cholecystectomy with the Argon Beam One coagulator].

The report is about argon embolism in a 37-year-old female patient during laparoscopic cholecystectomy and coagulation of a liver bed bleeding with the "Argon Beam One". The presented case report is to show that in spite of technical perfection and correct use of the Argon Beam One coagulator unfavorable anatomical conditions can cause life threatening gas embolism.

Adult

[Can endoscopic methods decrease the mortality and complication rate of bleeding stomach and duodenal ulcer? A study of the literature].

Bleedings from gastroduodenal ulcers still pose a major threat to health and life of a patient. Recent technical developments have provided the endoscopist with several methods for achieving hemostasis. In the present paper the results from clinical studies concerning interventional endoscopy shall be discussed. Criteria for the therapeutic approach for an individual patient shall be presented. Optimal results are possible if diagnosis and initial treatment are handled quickly by an experienced endoscopist. Early cooperation with the surgeon will further improve the outcome.

Duodenal Ulcer

[Chronic reflux esophagitis with endobrachyesophagus and multifocal adenocarcinoma].

In approximately 10% of all cases of endobrachesophagus a malignant degeneration occurs. A frequent endoscopic and bioptic control of the endobrachesophagus is the prognostic decision in order for a developing adenocarcinom to be identified in the early stages. Our casuistry demonstrates the problematic nature of the diagnostic and therapy of a multifocal adenocarcinom in an endobrachesophagus.

Adenocarcinoma

[Gastrointestinal leiomyosarcoma].

The clinical course of 12 patients was analyzed in a retrospective study; all of these patients were operated on a gastrointestinal leiomyosarcoma. The most common site of metastasis was the liver (33%). These data confirm that histologic grade, size and the extent of resection are the most important prognostic factors. Because the differential diagnosis between benign and malignant smooth muscle tumors is often quite difficult and a high risk of local recurrence the enucleation of these tumors is insufficient.

Adult

[Primary non-Hodgkin lymphoma of the stomach: diagnostic and therapeutic procedure].

It is reported on 13 patients with gastric non-Hodgkin's lymphoma, who underwent surgery between Jan 1st, 1984, and Sept 1st, 1987. Common symptoms included abdominal pain, weight loss and decline in health and strength. Endoscopy or barium studies had established the diagnosis of a gastric neoplasma in 12 cases. A total gastrectomy (n = 4) or a distal resection (B I n = 3, B II n = 5) was performed, depending on the size of the tumor and its location. Potentially curative resection was followed by radiotherapy in patients with high-grade lymphoma (stage I E). Patients with involvement of regional lymph nodes and advanced gastric lymphoma (stage II E1-IV E) underwent postoperative chemotherapy. So far follow-up (mean 25.3 months) revealed one case of relapse. These results confirm the value of surgical treatment in diagnosis, staging and treatment of primary gastric lymphoma. Survival in patients with advanced lymphoma and high-grade malignancy can be improved significantly by radical tumor resection, followed by multiagent chemotherapy and radiation.

Adult

[Diffuse eosinophilic gastroenteropathy].

Eosinophilic gastroenterocolitis is a very rare disease of the gastrointestinal tract. As a result, frequently the diagnosis is missed and/or symptoms get misinterpreted. Histological examination and blood analysis however support the finding of the correct diagnosis in most cases. We report here the case of a 47 year old female patient with diffuse gastroenterocolitis and we will comment the diagnostic problems.

Colitis

[The solid-cystic pancreas tumor].

Solid-cystic pancreas neoplasia is a rare condition mostly observed in young adults and women. We report three cases of this rare tumor. In all three instances the patients were young, slender women. The tumors were removed by total resection of the pancreas. In two cases these tumors were very large. In two cases we also observed criteria which could indicate that these tumors were malignant: the tumors had infiltrated the adjacent spleen and adjoining lymphnode or displayed a destroyed capsula. Until now, such infiltrative or malignant qualities have not been reported. That such criteria can be conclusively evaluated as an indication of malignancy, remains, however, unclear.

Adenoma, Islet Cell

[Camurati-Engelmann disease (progressive diaphyseal dysplasia). Differential diagnostic problems].

The Camurati-Engelmann disease is characterized by sclerotical hyperostosis, which can appear mainly bilaterally symmetrical at the diaphyses of the long bones, but also at all other bones of the skeleton. The Camurati-Engelmann disease is a rare one, up to now hardly more than 120 cases have been published. The rarity explains the fact that the disease is often misdiagnosed and mistaken for other bone diseases. This is a case report of a Camurati-Engelmann disease which was detected by radiological diagnosis. The problem of differential-diagnosis is described.

Aged

[Clinical aspects and therapy of benign pleural mesothelioma. A case report].

It is reported on a large benign monophasic fibrous mesothelioma. Despite its enormous size it was clinically silent and caused considerable problems in diagnosis and localisation. Computed tomography and arteriography suggested that the tumour, which was attached to the diaphragm and vascularized by strong vessels of the left gastric artery arose from the retroperitoneum. Therefore, falsely, the patient underwent initial laparotomy. At thoracotomy, the pedunculated tumour war easily removed. Histiogenesis and prognosis are evaluated in detail.

Diagnosis, Differential