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Biomedical subjects

R Bähr

Publications and source records attributed to R Bähr.

At least 73 records · Page 4Linked to original sources

[Echinococcosis in children--a case contribution].

Hydatid disease, or echinococcosis, is the most dangerous type of parasitosis in man in Europe. Two types are of clinical importance, namely, alveolar hydatid disease caused by Echinococcus multilocularis and cystic hydatid disease caused by Echinococcus granulosus. Cystic hydatid disease is characterised by an expansive growth via the formation of single or multiple cysts expanding in such a manner that they cause symptoms of space-occupying lesions, whereas the cysts of Echinococcus multilocularis undergo endogenous budding forming aggregates of innumerable small cysts honeycombing and even infiltrating the affected organ like a malignant tumour unlimited by the natural boundaries of the organ. Usually it takes about 10-15 years before the disease becomes manifest after the infection, because it is only then that compression of the surrounding organ tissue gives rise to symptoms. Hence, echinococcus disease is rare in children. The article reports on 7 children treated for Echinococcus granulosus. Complete exstirpation of the hydatid tissue is the treatment of choice. This is mostly achieved because of the benign nature of the growth. Chemotherapy remains an exception to the rule.

Adolescent↗

[Correlation between changes of bowel metabolism and of the small bowel mucosa after extensive small bowl resection- animal experiments (author's transl)].

The estimation of the bile acids in the liver and changes in the mucosa of the small intestine after extensive resection of the small bowel are reported. It is shown that through the implantation of an isoperistaltic segment a delay of the intestinal passage was achieved, which resulted in better contact between chyme and intestinal mucosa, as well as in a faster and more prominent hypertrophy of the mucosa of the small intestine. As a consequence of the hypertrophy, the resorption of bile acids in the small intestine was much improved.

Animals↗

[Congenital megacolon in adults].

Hirschsprung's disease is reported in 11 adults. About half of the patients had had previous surgery without relief of their symptoms. Diagnosis is established by a history of obstinate constipation since birth, the physical finding of abdominal distension and signs of large bowel obstruction without mechanical impediment. The definite diagnosis of Hirschsprung's disease rests on the demonstration of the absence of intramural ganglion cells in the rectum. The patients reported on underwent either the Rehbein-type operation or the Duhamel retrorectal pull-through. A three-stage procedure is recommended. Late results were satisfactory with both techniques provided there had been adequate resection of the aganglionic segment and anal dilatation to overcome the spasm of the internal anal sphincter.

Adolescent↗

[Choice of operative technic in the treatment of liver diseases].

Between 1974 and 1979 resection of the liver was carried out for malign or benign tumors in 42 patients. Lobectomy was performed in 17 and hemihepatectomy in 25 cases (11 times right-sided, 14 times left-sided). Hemihepatectomy with preliminary ligation of the vessels showed a lower rate of complication than the time-saving lobectomy. Mortality rate was 0% in left-sided hepatectomy, 12% in lobectomy, and 27% in right-sided hepatectomy. The cause of death was liver failure in three cases of hepatectomy because of preexisting damage of the remaining lobe showing no compensatory hypertrophy. In accordance with the literature, we conclude that right-sided hepatectomy can be performed only if hypertrophy of the left lobe is present.

Adult↗

[Computer tomographic and sonographic diagnosis of echinococcus (author's transl)].

In 33 patients (18 cystic echinococci, 15 alveolar) both methods produced the following findings which could be correlated with the pathological results: single or multi-centric lesions, sharp or indefinite demarkation and abnormalities in the shape and size of the liver. The sonographic findings were analysed with respect to the echo characteristics, whereas the computer tomographically demonstrated lesions were examined densitometrically in order to show calcification. Both methods demonstrate the pathological changes satisfactorily. Computer tomography is more effective in alveolar echinococcus lesions by showing the different types of calcification, whereas sonography provides a more accurate picture of the internal structure of the cysts in cystic echinococcus. Comparison of the methods in 19 patients examined by both showed a high accuracy in each method, but sonography was relatively poor in demonstrating lesions in the spleen.

Angiography↗

[Surgical treatment results in Crohn disease].

Between 1957 and 1978 122 patients with Crohn's disease were operated in the Surgical Department of the University of Tübingen. Follow-up examination showed a high recurrence of nearly 45%. 13 patients died during this time. A change of primary localisation from small intestine to colon was found. Surgery took place when drug therapy failed or complications like perforation, ileus or fistulae made it necessary. Resection must be radical. Immediate section for microscopic examination under surgery is seen as a possibility to reduce the relapse rate and avoid a more extensive intestinal resection. No malignant degeneration was noticed.

Adult↗