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Biomedical subjects

R Balmes

Publications and source records attributed to R Balmes.

3 recordsLinked to original sources
PubMed1995

[Subretinal manifestations as the chief findings in parasitic diseases in germany].

The most frequent intraocular manifestations of parasitoses in Germany and world-wide are retinochoroidal lesions of Toxoplasma gondii; worms are less frequent. In reports of four cases it is shown that demographic data, biomicroscopical hallmarks and the fecal wet-mounts are the most important parameters for a presumptive diagnosis, if no intraocular material can be isolated. The patients in this series lack systemic features and changes in the blood differential, probably due to the adequate alimentary state and lack of reinfestations.

Adult↗
PubMed1992

[Unilateral chronic granulomatous blepharitis as a leading symptom of Oriental cutaneous leishmaniasis in Germany. Giesma stain as rapid diagnosis and initial description of systemic therapy with gamma-interferon].

Nine months after leaving the Lebanon, a four-year-old immigrant boy presented with a 5 months history of blepharitis. The lesion remained therapy-resistant for aminoglycoside antibiotics. Six months later, the patient presented with an indolent granulomatous necrotizing purulent blepharitis and follicular conjunctivitis. Diagnosis was made by Giemsa stain and histopathology, which revealed amastigotes in macrophages consistent with the diagnosis of oriental cutaneous leishmaniasis. Therapy with systemic recombinant gamma Interferon, which is described for the first time in this disease entity, resulted in a successful primary healing of the cutaneous lesion. Self-healing epithelial keratitis was the only side-effect observed. Ophthalmologists in Germany should be aware of the differential diagnosis of oriental cutaneous Leishmaniasis in patients suffering from chronic granulomatous lid lesions of patients from countries endemic/epidemic for Leishmaniasis. Laboratory diagnosis is simple. Insights into the immunology of infection have made possible novel therapeutic avenues using gamma-Interferon being effective without serve side-effects and allowing for a good primary healing of the cutaneous lesions.

Biopsy↗