Sudden death in an infant with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency.
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Biomedical subjects
Publications and source records attributed to R Baraibar.
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A case neonatal meningitis by proteus mirabilis is presented. Echographic and CT scan studies were performed during clinical evolution, showing generalized brain abscesses appearances that needed surgical treatment. A ventriculo-peritoneal shunt was later practiced to correct hydrocephaly.
The authors reviewed the perinatal histories of 22 newborns malformations of the central nervous system, among 9,323 consecutive births in the last five years, with particular emphasis on the incidence and types of malformations, as well as the most important findings of the parents anamnesis. Prenatal ultrasonography is stressed out as an important tool in the precocious diagnosis of such a kind of malformations.
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Four newborn babies at term, with massive pulmonary haemorrhage associated with fulminant septicemia due to pseudomonas, are presented. The neonates died in the first day of life. The haematocrit and the proteic contents of the pulmonary effluent showed the existence of a pulmonary lesional edema. The histological findings in the four cases support this hypothesis. A revision of the etiopathogenic possibilities of the noncardiogenic pulmonary edema in the neonate is presented.
The case of a neonate born to a mother who was treated with indomethacin in the antenatal period is presented. Newborn presented, immediately after birth, severe respiratory distress syndrome, with cyanosis that remain unmodified by oxigenotherapy and mechanical ventilation. Clinical picture and analitic and radiographic findings, suggested persistent fetal circulation syndrome. It has been recently demonstrated that indomethacin is able to affect hemodynamic changes in neonatal period avoiding arteriolar dilatation and consequently, the fall of pulmonary vascular resistences. Administration of tolazoline was followed of rapidly improvement of the patient.
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