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Biomedical subjects

R Batres

Publications and source records attributed to R Batres.

4 recordsLinked to original sources
PubMed1995

Fortification of sugar with iron sodium ethylenediaminotetraacetate (FeNaEDTA) improves iron status in semirural Guatemalan populations.

A 32-mo-long, double-blind field study involving one highland control community receiving only vitamin A-fortified sugar and three vitamin A- and FeNaEDTA-sugar-fortified communities, two in the lowlands and one in the highlands of Guatemala, was undertaken to test the effectiveness of this approach in controlling iron deficiency. The communities' population ranged between 1200 and 17000. Sugar fortified with 1 g FeNaEDTA and 15 mg retinol as retinyl palmitate/kg was stable, did not segregate, and was well accepted by the communities. The impact of fortification on iron nutrition was estimated at 8, 20, and 32 mo of intervention. All pregnant women and subjects with severe anemia received supplements or treatment and were excluded from the analysis. Iron stores in the fortified communities increased significantly except for women 18-48 y of age in one lowland community and > 49 y in the highland community. Iron stores in the control community remained unchanged except for a rise among adult males.

Adolescent↗
PubMed1985

Homeostatic mechanisms in the utilization of exogenous iron in children recovering from severe malnutrition.

We evaluated the role of initial iron stores on iron accumulation during recovery from severe edematous protein-energy malnutrition in children. Twenty-six preschool children were divided in two groups according to their initial iron reserves, as estimated from serum ferritin concentration, using a cutoff criterion of 30 ng/ml. The low ferritin (LF) group had a mean serum ferritin level of 12 +/- 8 ng/dl, and the high ferritin (HF) group, 86 +/- 32 ng/dl. Both groups had similar degrees of malnutrition and of anemia, as defined by hemoglobin concentration. All children received an adequate therapeutic diet and 60 mg iron daily as ferrous sulfate. The recovery of biochemical and anthropometric indicators of nutritional status, as well as of hemoglobin concentration, was similar in both groups. On the contrary, the LF group showed a marked increase in serum ferritin concentration from the onset of treatment, whereas the HF group had a net decline in this parameter by 30 days, and a stable level thereafter. The difference in serum ferritin concentration between groups was maintained until day 60, and both groups ended the study (90 days) with similar levels. Estimation of the utilization of exogenous iron from changes in total-body iron during the first 60 days of recovery showed the LF group to retain an average of 9.3% of iron intake, whereas the HF group retained only 1.4%.(ABSTRACT TRUNCATED AT 250 WORDS)

Anemia, Hypochromic↗
PubMed1982

The effect of temporary venous occlusion on trace mineral concentrations in plasma.

The effects of short-term venous occlusion on plasma concentration of trace minerals--zinc, iron, and copper--were studied in normal volunteers. In one experiment, antecubital vein blood samples were drawn simultaneously from both arms of 14 subjects while their left arms remained free and their right arms had been occluded from 60 s at 40 mm Hg pressure. Statistical comparison of paired samples showed a significant increase in zinc (p less than 0.05) and iron (p less than 0.001), but not copper concentrations in plasma from the occluded extremity. The mean increase in concentration in the right (ligated) arms with respect to the left (unligated) arms was 3.7 and 24.6%, for zinc and iron, respectively. In a second experiment, simultaneous blood samples were drawn from five subjects with neither arm occluded. No significant difference between right and left was observed. Thus, application of tourniquets during the sampling of venous blood for trace mineral analysis introduces a nonrandom factor. Standardization of sampling techniques is essential to overall reliability of trace mineral determinations.

Adult↗