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Biomedical subjects

R Beck

Publications and source records attributed to R Beck.

At least 163 records · Page 9Linked to original sources

[Diagnosis, treatment and results of surgically treated fresh exterior ligament ruptures of the upper ankle joint].

Among 355 recent ruptures of the fibular ligaments which had been operated in seven years - by altogether 3413 traumas of supination and of distorsion - 271 patients have had a follow-up examination. A reduction of the mobility was found in 9% of the cases, a clinically demonstrable opening of the ankle was found in 11% of the cases. 11% of the cases specified complaint by burden. 95% of the operated patients attended sporting activities. The opening of the ankle was the same as against the other side in 79% of the cases - proved by radiological examination; there was a slight increased opening of the ankle compared with the non-operated ankle in 15% of the cases, an increased opening of the ankle was found in 6% of the cases. Subjective complaint and clinical and radiological findings were taken into consideration of the opinion of the results. We found good up to very good results in about 90% of the cases. The treatment of the recent rupture of the fibular ligaments only can consist in a combined suture including a following cast - in agreement with other authors; nevertheless an isolated rupture of the anterior fibulotalar ligament does not compel to operate all cases.

Adolescent↗

Transcutaneous PO2 monitoring during a Himalayan ascent.

Transcutaneous PO2 (PtcO2) measurements were taken daily on seven subjects during two nine day ascents of the Himalayas to an altitude of 4,579 meters. Five of the subjects lived in areas under 450 meters (Group I), while two subjects lived at an altitude of 3,100 meters (Group II). The PtcO2 values decreased with increasing altitude. The Group II subjects had PtcO2 values greater than the Group I subjects and the difference became greater with increasing altitude. The linear regression lines of PtcO2/pbO2 to Group I during ascent and decent were lower than the regression line for Group II (PbO2 is the barometric oxygen partial pressure). The regression line for Group I data during the second half of the trek approached the data for Group II. We conclude that acclimatization to high altitude is possibly associated with increasing peripheral tissue oxygenation as assessed by PtcO2 values.

Acclimatization↗

A human umbilical cord with four arteries.

An unusual case of a newborn infant with four umbilical arteries is presented. Multiple catheterizations revealed that triplication of the right umbilical artery was responsible. There were no associated malformations, and follow-up at 9 months of age revealed age-appropriate growth and development. This case extends the spectrum of observable umbilical artery anomalies.

Humans↗

[Monoamniotic twin pregnancy with knotted umbilical cords].

Monoamniotic twins and true knots of the umbilical cord have a rare occurrence, their coincidence, however, is frequent by more than a half of the observations. There is a case report. The complication could be recognized by cardiotocographic control of the fetuses and both viable children had been delivered by a well-timed cesarean section. It is demanded a premature diagnosis of the twin pregnancy by ultrasonographics B-mode with evidence of the membranes, greatest care to surveillance of out-patient and hospitalized pregnant women, cardiotocographic control of the twins sub partu and generous indication for cesarean section.

Adolescent↗

[Pancreatic pseudocysts. Treatment and results].

179 operations were performed for pseudocysts of the pancreas between 1960 and 1982. Basing on this experience the various methods of surgical treatment and the corresponding indications are discussed, and their advantage and disadvantage comparatively represented. In the treatment of very small cysts we suggest an expecting attitude, their statement must be controlled. In case of surgical treatment the enteroanastomosis in the form of a pancreatocystojejunostomy is supposed to be the best alternative.

Humans↗

Perinatal and neonatal aspects of maternal idiopathic thrombocytopenic purpura.

The pregnant woman with idiopathic thrombocytopenic purpura (ITP) and her fetus-neonate present a number of challenging issues for both the perinatologist and neonatologist. A review of these issues within a single format is helpful because of the widely scattered nature of the pertinent information in the medical literature. Maternal ITP is described herein as chronic, idiopathic, immune thrombocytopenic purpura, and the multiple interactions between ITP and pregnancy are detailed. The chief effect of maternal ITP on the fetus-neonate is thrombocytopenia, which occurs in approximately 37% of infants born to mothers with ITP. Using available literature, the pathophysiology, natural course, and therapy for maternal ITP-induced neonatal thrombocytopenia are described. Because affected infants may be severely thrombocytopenic at birth and at risk for hemorrhagic symptoms secondary to the stress of vaginal delivery, cesarean section is advocated as the preferred route of delivery for mothers with ITP. This approach is controversial, however, principally because many cesarean sections are productive of unaffected or mildly affected neonates. The predelivery use of fetal blood sampling and the presence of maternal circulating (unbound) antiplatelet antibody in this setting may provide the perinatologist guidance as to the appropriate delivery route for the at-risk thrombocytopenic infant.

Brain Diseases↗

Epidermal growth factor-urogastrone receptors in normal human liver and primary hepatoma.

Epidermal growth factor-urogastrone (EGF-URO) receptors have been demonstrated in rodent liver and modulation of ligand binding during transformation has been shown in a variety of study systems. A patient presented with a resectable primary hepatoma arising in a histologically normal liver. We carried out ligand binding studies using 125I-EGF and homogenates or plasma membrane preparations of normal and hepatoma tissues. EGF-URO receptors were demonstrated in normal human liver; half-maximal binding occurred at 2.5 X 10(-9) M 125I-EGF. Binding decreased in association with hepatoma formation. These results provide initial evidence that EGF-URO receptors exist in human liver and that ligand binding changes accompany hepatoma formation in man.

Carcinoma, Hepatocellular↗

[The endoesophageal intubation--a favourable palliative operation of malignant stenoses in the esophagus-cardia-region? (author's transl)].

131 patients with malignant stenoses in the esophagus-cardia-region were palliatively treated with an endoprosthesis. The procedure in these patients of an average age of 65.5 years is described. The average in patient time is 22 days. The postoperative mortality is 22.9%. The complications specific for the operation method are dislocation of the prosthesis, perforation of the esophagus, bleeding and occlusion. 74.4% of the patients subjectively considered the operation successful.

Adult↗

[Extra-uterine twin pregnancy. Observation of a case of bilateral tubal pregnancy and literature review].

Literature was reviewed for the rare case of extra-uterine twin pregnancy, with particular reference being made to a real case of bilateral tubal twin pregnancy. Topographic aspects and age of pregnancy should be taken into account for definition. Aetiological factors and clinical peculiarities are discussed. The author holds that so far less than 100 cases have been reported in which bilateral tubal twin pregnancy had been safely established.

Adult↗