Biomedical subjects
Publications and source records attributed to R Bellosta Ferrer.
The authors describe the experimental results of administering BCNU combined with hyperthermia upon the growth of sarcoma 180 of the mouse. Best results were obtained employing the combined therapy than using BCNU or hyperthermia alone, and hyperthermia was necessary in all cases where a curative effect was attained.
Several investigations carried out recently have shown that cancer radiotherapy obtains better results in some tumors when multiple daily fractionation is employed. The authors review the different kinds of dose fractionation and the obtained results.
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The authors make an experimental study of the weight evolution and survival rate of sarcoma 180-bearing C3H mice treated by combinations of radiotherapy and hyperthermia. The body weight increased progressively in control animals. The weight increase was less marked under the effect of radiotherapy, hyperthermia, and radiotherapy plus hyperthermia, in decreasing order. While tumor-bearing control animals died after an average of 26.6 days, 3.33, 16.67 and 76.67 per cent of the mice treated respectively by radiotherapy, hyperthermia, and radiotherapy plus hyperthermia were living after 90 days.