[Chronic arthritis of the elbow caused by sarcoidosis].
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Adult↗
Biomedical subjects
R Bennis
Publications and source records attributed to R Bennis.
Diffuse arthralgia and myalgia as the first manifestation of benign myeloradiculopathy due to cytomegalovirus infection in an immunocompetent patient.
CMV-induced neurological manifestations are uncommon, especially in immunocompetent subjects. We report a case of CMV-induced myeloradiculopathy with a favorable outcome in an immunocompetent patient who presented with diffuse myalgia and inflammatory polyarthralgia. Presence of both peripheral and central neurological abnormalities with monocytosis and positive serological tests in the blood and cerebrospinal fluid established the diagnosis. Mixed neurological involvement is rare during CMV infection and usually occurs in association with a deficiency in immunological responses.
Adult↗
Sciatica as the first manifestation of a leiomyosarcoma of the buttock.
We report the case of a 22-year-old woman who was admitted for inflammatory right-sided sciatica with a decline in general health. Laboratory tests showed severe inflammation. Ultrasonography and computed tomography of the buttock and pelvis demonstrated a large tumor in the deep muscles of the right buttock, with an intrapelvic component that displaced the pelvic organs without invading them. Histologic examination of a biopsy specimen taken via the buttock established the diagnosis of leiomyosarcoma. Surgery by a pelvic approach allowed partial resection of the tumor, which was seen to invade the sciatic nerve. Radiation therapy was given. Six months later the residual tumor was considerably larger and the patient's general health had deteriorated further. Leiomyosarcomas are rare tumors whose diagnosis rests on histologic examination of biopsy or surgical specimens. The treatment is surgical. Recurrences are seen in 40 to 60% of cases, and metastases in 27 to 60%. The place of radiation therapy and chemotherapy in the treatment of leiomyosarcoma remains unclear.
Adult↗
[Tabetic joint diseases. 4 cases].
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Humans↗
Psoas abscess complicating Crohn's disease.
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Adolescent↗
[Objective evaluation of sclerodermic skin using the slip-test. Results and validation with 30 patients and 60 controls].
The slip test is a non-invasive way to objectively evaluate the extent of scleroderma by measuring the "slipping" of the skin over an underlying bone. The results obtained in 30 scleroderma patients and 60 controls (178 tests due to multiple measurements) were analyzed to determine which test sites show a significant difference between patients and controls (Student's t-test) and which sites are the most discriminating for the diagnosis of the disease (multivariate analysis). Patient values were clearly distinct from those of controls. The best sites (defined by p < 0.05) were: the mandible, the second and first phalanges of the middle finger, the hands, the forearms, the epicondyles, the sternum, the iliac crests, the patellae, the tibias (the upper and lower fourths) and the feet; in all, 23 sites to which can be added the opening of the mouth (measurement of the maximal interlabial distance), which proved to be a reliable parameter. Multiple regression analysis yielded an equation that identified patients with scleroderma based on 4 variables (right forearm, right iliac crest, sternum and right rib). The slip test is thus the first reproducible quantitative test able to confirm and quantify clinical impressions in scleroderma. It is entirely able to objectively monitor the evolution of the disease under treatment. Nevertheless, complementary studies are needed to verify whether the slip test, which can be performed in 20 minutes during an office visit, can be used advantageously in the routine clinical evaluation of scleroderma.
Adult↗
[Behçet's disease. 316 cases].
The authors have reviewed the records of 316 patients with Behcet's disease diagnosed between 1981 and 1989 in the Internal Medicine Department of Casablanca's University Hospital, Morocco. Males aged between 20 and 40 years (78 percent) were most frequently affected (71 percent of the cases). All patients presented with muco-cutaneous lesions, including aphthous stomatitis (100 percent) and genital ulcers (85 percent). Skin hyperirritability was present in 77 percent. Ocular lesions were frequent (72 percent) and led to blindness in 88 patients. Articular manifestations occupied third rank in our series, with 60 percent of the cases. Three patients showed polyarthritis deformans, with destructive lesions in two cases and associated with Sjögren's syndrome in one case. Thrombophlebitis was present in 69 patients (superior vena cava thrombosis in 8 patients and Budd-Chiari syndrome in one), and it was complicated by pulmonary infarction in 6 cases. Other vascular lesions included middle cerebral artery thrombosis (1 case), cerebral arterial aneurysm (1 case) and pulmonary arterial aneurysm (1 case). Neurological manifestations were present in 50 patients (16 percent), in 13 of them related to mild intracranial hypertension. Ulcerative colitis was diagnosed in 2 cases and proteinuria in 4 others, with a nephrotic syndrome in 2 cases.
Adolescent↗
[Articular manifestations of Behçet's disease. Apropos of 73 cases].
The authors report 73 cases of Behçet's disease with articular manifestations. Polyarthritis, generally considered to be rare, was found in 20.5 per cent of cases in this series. The unusual features are illustrated. Amongst them, two cases presented deforming and destructive lesions, which have been only exceptionally reported in the literature. A third case is unusual because of the association of Gougerot-Sjögren's syndrome with Behçet's disease and polyarthritis deformans. No cases of ankylosing spondylitis were observed. Lastly, the data of this series are compared with those of the literature.
Adult↗
[Acid-base imbalance].
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Acid-Base Imbalance↗
[Desensitization by autologous saliva and Behçet's disease].
Among 240 patients with Behçet's disease seen in the Internal Medicine Department of the Ibnou Rochd University Hospital, Casablanca, between January 1981 and April 1988, 44 were selected to study the effects of desensitization by autologous saliva on oral and genital aphthae and on articular manifestations. Thirty of these 44 patients received gradually decreasing dilutions of their own saliva, and 14 control patients received physiological saline. Injections were administered intradermally twice a week during 15 weeks, then once a week during one year, so that the study lasted one and a half year, from October 1986 to April 1988. No improvement of the arthritis was observed, whereas the oral aphthae were improved in 50% of the patients desensitized by their own saliva. This percentage would have raised some hopes for the treatment of these sometimes disabling lesions were it not for the fact that 50% of the controls were similarly improved. This suggests that desensitization by saliva has a placebo effect.
Behcet Syndrome↗