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Biomedical subjects

R Berube

Publications and source records attributed to R Berube.

5 recordsLinked to original sources
PubMed1992

Reversed-phase high-performance liquid chromatography-thermospray mass spectrometry of radiation-induced decomposition products of thymine and thymidine.

High-performance liquid chromatography-thermospray mass spectrometry was applied to the analysis of various radiation-induced decomposition products of thymidine including N-(2-deoxy-beta-D-erythro-pentofuranosyl)formamide and the various diastereomers of 5,6-dihydroxy-5,6-dihydrothymidine, 5-hydroxy-5,6-dihydrothymidine and 5,6-dihydrothymidine. This method combines high sensitivity and product resolution, rendering it particularly useful for monitoring the formation of radiation-induced base damage within DNA.

Chromatography, High Pressure Liquid↗
PubMed1983

Comparative thermoresistance of two biological indicators for monitoring steam autoclaves. I. Comparison performed in a gravity BIER/Steam Vessel.

The thermoresistance of two biological indicators (BIs) for steam sterilization control (Swedish spore tablets and Attest No. 1242 BI) was compared at 121 degrees C and at 134 degrees C, saturated steam, in a special test autoclave (a gravity BIER/Steam Vessel). In this autoclave, three lots of Attest No. 1242 BI (ABI) demonstrated longer survival exposure times than did the three lots of the Scandinavian BI (SBI) tested while the survival-kill range was approx. the same. Also, the ABI had higher D121 degrees C- and D134 degrees C- values based on fraction-negative tests. The D121 degrees C-value of approx, 1.5 min as suggested by the European Pharmacopoeia, was met by both BIs. The larger spore population and the package configuration of the ABI units contribute to the higher thermoresistance of the ABI in the gravity BIER/Steam Vessel.

Geobacillus stearothermophilus↗
PubMed1968

Simple method of remove completely ciliate protozoa of adult ruminants.

Dioctyl sodium sulfosuccinate (Aerosol OT) has been used in a remarkably short period to obtain rumen ciliate-free cows. Two 30-g doses of Aerosol OT given on consecutive days appeared to effectively eliminate all types of rumen ciliate protozoa without harming the health of the host animal. Measurement of the rumen metabolic parameters of gas production, carbon dioxide to methane ratio, pH value, volatile fatty acids, ammonia, and in vitro cellulose digestion, along with total amylolytic streptococci counts of the rumen contents, showed that conditions in rumens of defaunated animals are normal 4 days after such treatment. It appears that such animals may be used in ruminal studies that require defaunated animals.

Animals↗
PubMedDate not supplied

A peer review program for professional nurses.

Within the past 3 years, the Division of Nursing in a large medical center implemented a career ladder and a professional practice model. Peer review was identified as a critical component for the success of these two initiatives and maturation of the model. Limitations in the conduct of peer review among the professional nursing staff centered around the lack of a coherent process. The Coordinating Council, the governing body of the professional nursing staff, formally recognized the accomplishments of a Quality Improvement team and directed the team to implement and evaluate a process of peer review. The development and implementation of peer review as experienced by this Quality Improvement team is described in this article. The process and structure of peer review and specific continuous improvement tools used by the team in developing this process are reviewed.

Career Mobility↗