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Biomedical subjects

R Bessis

Publications and source records attributed to R Bessis.

34 records · Page 2Linked to original sources
PubMed1988

[Nul telediastolic flux. Prognostic value].

42 fetuses over a period of 2 1/2 years have presented with absent end-diastolic velocity. In 6 of these cases the measurements that had been carried out before the 22nd week of pregnancy with later normalisation of the Doppler velocities did not constitute a poor prognostic sign. On the other hand, absent end-diastolic velocity after the 22nd week (36 fetuses) was a sign of chronic fetal distress. The fetal mortality was 33.2%. 19.45% of the infants had chromosome abnormalities and only 58% of these children were alive and healthy. 74% of the live infants were delivered by caesarean section. With these results we think that absent end-diastolic velocity is a simple diagnostic sign, but it warns us that we should carry out tests for the fetal karyotype.

Adult↗
PubMed1988

[Prenatal diagnosis and genetic diseases of the lung].

Currently two genetic pulmonary disorders can be diagnosed before birth: alpha-1-antitrypsin deficiency and mucoviscidosis. For the latter there are two possible diagnostic techniques: first a study of the intestinal enzymes of the amniotic fluid, a reliable method only at the 18th week, and also a study of DNA markers (ADN) of the trophoblastic cells using molecular biological techniques: this can be performed from the 10th to 11th week of pregnancy but presupposes a family study in which there is already a subject suffering from the disorder. Foetal echocardiography enables various pulmonary abnormalities to be detected: pleural effusion, cyst, pulmonary hypoplasia and other disorders. This technique however has some limits, at least at present. Most often these severe malformations are revealed at birth such as respiratory distress or stillbirth. Adenomatous cystic malformations or congenital lobar emphysema, a posterior diaphragmatic hernia, and oesophageal atresia with oesophagotracheal fistula are the most frequent and are curable surgically.

Amniotic Fluid↗
PubMed1983

[Caffey's disease with antenatal onset].

The authors report one case of Caffey's syndrome with antenatal onset. X-ray of the uterus, that was required because of an hydramnios, led to the diagnosis. Ultrasonography showed the fetal anomalies. Data in the literature concerning case reports of Caffey's syndrome with antenatal onset show a moderate incidence of familial cases.

Female↗
PubMed1982

[Intra-uterine detection of atrio-ventricular block in two children whose mother had Sjögren's syndrome].

A woman with isolated juvenile Sjögren's syndrome gave birth, at 3 years' interval, to two children with complete atrio-ventricular heart block (AVB). This is the first published case of AVB in children of mothers with Sjögren's syndrome without any clinical and laboratory evidence of connective tissue disease, notably lupus. Ultrasonography showed that the AVB was acquired in utero and occurred during the 23rd week of gestation. In both children the AVB was isolated, without any symptom of congenital malformation of the heart; there were no abnormalities of conduction in the mother. Early corticosteroid treatment of the mother's disease had no beneficial effect on AVB in the foetuses. Attempts to reproduce the condition experimentally met with failure.

Adult↗
PubMed1981

Monitoring of ovulation induction with human menopausal gonadotropin and human chorionic gonadotropin by ultrasound.

Ovarian follicular growth was monitored by ultrasound and plasma estradiol levels in 43 cycles of 27 patients. These women were treated with human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG) for anovulation or poor cervical mucus. Ultrasonography can help to prevent multiple pregnancies by allowing the withholding of the ovulatory injection of hCG if the number of mature follicles is too great. Nevertheless, mild to moderate hyperstimulation cannot always be prevented; it is sometimes the price one has to pay to obtain a pregnancy. Giving a direct view of follicular maturation, this method can be helpful in the determination of the best time for the induction of ovulation.

Chorionic Gonadotropin↗
PubMed1979

The frequency of ovular resorption during the first trimester of twin pregnancy.

A follow-up of 78 twin pregnancies diagnosed in the first trimester indicated that early ovular resorption occurred in 63% of spontaneous and 64% of Clomiphene-induced gestations, so that singletons were born. No failure was observed in the 12 twin conceptions following administration of gonadotropins or Cyclofenil.

Chorionic Gonadotropin↗
PubMed1979

Foetal twin ultrasound biometry.

Biparietal diameter growth differs considerably in the twin gestation compared to the singleton gestation; thus the use of a specific standard is recommended. A shift toward lower values is noticed in monochorial twins. In the case of the abdominal diameter growth, instead, no significant difference is found between twins and singletons.

Cephalometry↗