Biomedical subjects

R Bickerton

Publications and source records attributed to R Bickerton.

4 recordsLinked to original sources

PubMed1994

A case of profound iron deficiency anemia owing to corrosive esophagitis in a 20-year-old developmentally delayed male.

The level of severe compensated iron deficiency anemia incompatible with life is not defined in the pediatric or adolescent literature. A hemoglobin of 1.5 gm/dl in an older adolescent with few physical symptoms is distinctly unusual. A case of profound iron deficiency anemia in a 20-year-old developmentally delayed male is the subject of this brief report. There were only subtle physical findings in spite of this severe anemia. The anemia was the result of corrosive esophagitis associated with a hiatal hernia and reflux. Physicians dealing with developmentally delayed adolescents should be aware of the fact that a severe anemia may develop, and such individuals should be periodically screened for anemia, melena, hematochezia, and hematemesis.

Adult↗

PubMed1992

Intrathecal baclofen for intractable spinal spasticity--a double-blind cross-over comparison with placebo in 6 patients.

A group of six subjects with intractable spinal spasticity completed a double-blind cross-over paradigm in which they received two intrathecal bolus injections of baclofen solution five hours apart on two different days and two intrathecal bolus injections of placebo saline five hours apart on two other days. Each subject was repeatedly tested with a battery of clinical and physiological tests. In contrast to the placebo injections, the group responded to the baclofen injections with subjective and objective, clinically significant improvement in parameters of spasticity in their lower limbs, including muscle tone, frequency of spasms, hyperreflexia and passive range of joint motion. Furthermore, this improvement was maintained following thirty consecutive days of intrathecal bolus injections of baclofen at a fixed dose.

Adult↗

PubMed1984

Free histamine in nasal polyp fluid.

Nasal polyp fluid was extracted from 52 patients to evaluate histamine levels and compare them with the corresponding serum levels. Large but variable amounts of histamine were found in polyp fluid (124-7600 ng/ml) which was between twenty and a thousand times the serum level. There was no significant difference between the polyp histamine levels in patients with a history of asthma, aspirin hypersensitivity, hay fever and positive skin tests.

Aspirin↗

PubMedDate not supplied

Identifying and treating ocular emergencies.

The nurse's role in addressing ophthalmic emergencies can determine the urgency of the treatment and, in some cases, the final visual outcome. It is important to understand the spectrum of traumatic eye injuries so the patient will be better cared for and the appropriate treatment regimen will be started before permanent vision loss occurs. Assessing visual acuity is key; it must be documented, and if visual acuity cannot be obtained immediately, this fact also must be recorded.

Emergencies↗