Biomedical subjects
R Blight
Publications and source records attributed to R Blight.
Early changes in peripheral retina following concussive ocular injuries: an experimental study.
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Histological changes in the internal retinal layers produced by concussive injuries to the globe. An experimental study.
The level of lesions within the human retina causing transient post-concussive retinal opacification (Berlin's oedema) remains unclear, as histological examination of this tissue is rarely possible before the ophthalmoscopic changes resolve. Studies in vivo of retinae in man and experimental animals previously subjected to blunt, nonperforating mechanical injuries suggest that the development of intracellular oedema may be the principal reason why the retina becomes opaque. The retinae of experimental animals (pigs), whose eyes had been subjected to concussive injuries, were examined histologically after the removal and fixation of the globes, at periods ranging from a few minutes to 7 days after trauma. Disturbances were noted in the inner retinal layers immediately after trauma, which included transient swelling of the mitochondria in the nerve fibres lasting for only a few hours, and marked intracellular oedema of the glial elements which took 2 to 3 days to resolve.
Changes occuring in the nerve fibre layer of pigs' retinae following concussive injuries to the globe.
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Structural changes in the outer retinal layers following blunt mechanical non-perforating trauma to the globe: an experimental study.
Structural changes in the external retinal layers of pigs' eyes that had previously been subjected to blunt non-perforating mechanical injuries have been described. Within minutes of trauma fragmentation of the photoreceptor outer segments and damage to the retinal pigment epithelium was recorded in areas of retina adjacent to the missile impact site on the sclera. One week after injury the disrupted photoreceptor outer segments disappeared, and the inner segments came to lie adjacent to the retinal pigment epithelium. Evidence of regeneration of photoreceptor outer segments was noted 2 weeks later.
Electrophysiological and pathological investigation of concussional injury. An Experimental study.
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Chemical studies on experimental allergic encephalomyelitis. Peptide as the common denominator in all encephalitogenic 'antigens'.
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