Biomedical subjects

R Boerngen

Publications and source records attributed to R Boerngen.

4 recordsLinked to original sources

PubMed1980

Gender differences in open-field behavior as a function of age.

Male and female rats were observed in an open field at 30, 45, 60, 90, and 120 days of age. Thirty- and 45-day-old rats of both genders presented similar defecation, ambulation, and rearing scores. From 60 days on the male rats showed higher defecation scores and less ambulation and rearing than did the females. The gender difference observed in the adult rats reflected a decrease of defecation by females and a decrease of ambulation and rearing by males when compared to the earlier ages.

Aging↗

PubMed1980

The excitatory component of ethanol in mice: a chronic study.

The effects of chronic administration of initially depressant, ineffective and excitatory doses of ethanol on the locomotor activity of mice was studied. The results showed that (1) an excitatory effect of ethanol is observed after tolerance develops to its depressant action; (2) the effect induced by an initially excitatory dose of ethanol became more pronounced with chronic exposure to the drug; and (3) tolerance to the excitatory effect was not reached after 60 days of ethanol treatment.

Animals↗

PubMed1980

Sex differences in the response to apomorphine in rats.

The response of male and female rats to the hypothermic and verticalization effect (climbing behavior) induced by different doses of apomorphine was studied. A clear sex difference was observed, males showing more verticalization than females. Conversely the females showed a greater decrease in body temperature than males. The verticalization response was also studied in rats of both sexes at seven different ages, varying from 15 to 100 days. At the earlier ages, both groups presented low levels of verticalization. Mature males (60-100 days of age) increased the verticalization response to apomorphine.

Aging↗

PubMed1980

Comparison of the acute effects of sugar cane distillates and ethanol in mice.

The acute effects of 4 different brands of the most popular Brazilian alcoholic beverage, the so called "cachaças" (distilled product of sugar cane), were measured through the loss of the righting reflex and the rotarod test. The effects induced by the cachaças were greater than it could be predicted through the ethanol content alone.

Alcoholic Beverages↗