PubMed Health⌕ Search

Biomedical subjects

R Boja

Publications and source records attributed to R Boja.

8 recordsLinked to original sources
PubMed2001

Differential expression of GL7 activation antigen on bone marrow B cell subpopulations and peripheral B cells.

GL7 was originally described as a 35-kDa late activation antigen on mouse T and B cells. GL7 expression has also been demonstrated on thymocytes, germinal center B cells and some neuronal cell types. Flow-cytometry and immunohistochemistry were used to follow changes in the expression of GL7 during B cell development, amongst B cell subpopulations and various anatomical locations. GL7 is expressed as early as the pro-B cell stage and increases up to the pre-B-I stadium. Expression remains high on pre-B-II and on immature B cells, although slightly decreases during maturation. GL7 is almost completely downregulated when IgD appears on the cell surface. On the periphery only a few B cells are positive and these cells are almost exclusively found in the sIgD- germinal center areas of lymph nodes and spleen. The staining pattern of GL7 is very similar to that of PNA in the lymph nodes but in the bone marrow we have found both B220+PNA+GL7- and B220+PNA+GL7+ populations, showing that GL7 and the antigen recognized by PNA are different. After in vitro stimulation, the GL7(hi) B cell population has also been found to be IgD negative. Functional comparison between in vitro activated and MACS sorted GL7(hi) and GL7(lo/-) spleen B cells of immunized mice showed significantly higher specific and total antibody production as well as antigen presenting capacity in the GL7(hi) population.

Animals↗
PubMed1992

Emergency percutaneous nephrostomy in the septic kidney.

From 250 upper tract obstructive uropathy cases we have studied 64 patients hospitalized with toxico-septic shock. The constant symptom was arterial hypotension. Other 3 patients with long-standing urinary infection due to lithiasis developed this dreaded complication after PNL (staghorn stones-2, pyelic stone-1). In complicated obstructive uropathy cases associated with toxico-septic shock, percutaneous nephrostomy for high urinary derivation in emergency is usually made under local anaesthesia. Its aim is rapid and efficient clearance of kidney obstruction, with minimal damage for the patient; then it is followed by strong antibiotherapy associated with other reanimation and intensive care measures. There were 11 deaths. The stone generating obstructive uropathy was removed subsequently, after the improvement of biological constants and general state of the patient, under the protection of percutaneous nephrostomy.

Acute Disease↗
PubMed1984

Anterograde urethrotomy, a new method for internal urethrotomy.

The authors elaborated a new device permitting to perform internal urethrotomy for urethral stricture in an anterograde way, even in cases where optical retrograde urethrotomy could not be applied. The new device is similar to a bladder biopsy forceps with a diameter of Ch 5. Its cutting knife is movable. It can be used with Sachse's urethrotome, inserting it in its guide channel with closed knife and passing it through the stricture. By opening the knife, anterograde urethrotomy can be performed. Out of 145 urethrotomies, this method was utilized in only 3 cases.

Humans↗
PubMed1983

Original transvesical prostatectomy.

Starting out from a series of theoretical considerations, and checked clinically, the authors describe an original technique for prostatic adenomectomy, being more efficient in limitation of surgical haemorrhage, urinary infection and postoperative hypogastric fistulae. The operative technique and its results in comparison with classic techniques are presented.

Humans↗
PubMed1978

Improved suprapubic vesical drainage in transvesical prostatectomy.

An improved drainage is used in transvesical prostatectomy in order to avoid urinary retention after removal of the Novak-type suprapubic drainage with bladder neck cerclage haemostasis (described by some authors in 1975). The causes of urinary retention are analysed, the drainage technique as well as the mechanisms eliminating the above-mentioned complications are described.

Humans↗
PubMed1977

[Technic of transvesical suprapubic adenomectomy for the control of hemorrhage and urinary infection].

The advantages of our method: 1. By omission of the urethral catheter the infection is nearly completely avoided. 2. It guarantees a good haemostasis. 3. It reduces the intraoperative and later complications of adenectomy (infection and anaemia). 4. It facilitates the postoperative treatment. 5. One avoids urethritis and strictures caused by the urethral catheter. 6. It shortens the postoperative period of rest. 7. One economises medicaments (antibiotically, antianaemically). 8. The possible break of the catgut thread at its removal is of no danger, as it is resorbed.

Drainage↗