Biomedical subjects

R Bojalil

Publications and source records attributed to R Bojalil.

21 records · Page 2Linked to original sources

PubMed1988

Cohort study of intestinal infection with campylobacter in Mexican children.

A cohort of 179 children under 5 years of age from a low-income urban community was followed up for a year to determine the incidence of symptom-producing and of diarrhoea-free campylobacter intestinal infections, and thus their illness-to-infection ratio. 66% of all children had at least one campylobacter infection, one-third of these being associated with diarrhoea. The annual incidence of all campylobacter infections was 2.1 episodes per child. The incidence was inversely related to age (r = -0.78 p less than 0.02). The illness-to-infection ratio, which in infants younger than 6 months was 1:2, was negatively associated with age (r = -0.7, p less than 0.02). Only symptom-producing infections occurring early in life seemed to protect against subsequent infections.

Age Factors↗

PubMed1986

Reliable serology of Taenia solium cysticercosis with antigens from cyst vesicular fluid: ELISA and hemagglutination tests.

New levels of reproducibility and sensitivity have been achieved in the detection of anticysticercus antibodies in human sera by using cysticercus vesicular fluid as the source of antigens for both ELISA and hemagglutination assays. Reproducibility both between tests on a serum and between similar sera was significantly improved over typical results using antigens from whole parasite extracts. Sera collected from uninfected individuals in endemic areas gave somewhat elevated values over those collected in nonendemic areas. This necessitated the use of a higher threshold in endemic areas to avoid false positives. With the threshold appropriate for a nonendemic area, both ELISA and hemagglutination were sensitive enough to detect infection in 95% of cases. With the threshold value for sera from an endemic area, these sensitivities were reduced to 80%-90%. A prominent 103-Kd protein of vesicular fluid, not related to antigen B, elicited the strongest antibody response in neurocystercotic patients.

Antibodies↗

PubMedDate not supplied

[Immune response or tolerance. Cellular selection by the thymus].

There is currently a very active research on the mechanisms that give rise to the cell selection of lymphocyte precursors by the thymus. This selection is basic for the process of formation of the repertoire of T cells with which an organism is potentially capable of developing an immune response to a foreign antigen, and not doing so when encountering its own antigens. This work pretends to detail some recent advances in the knowledge of the process by which cells are positively or negatively selected by the thymus, to give rise to the T cell repertoire of an individual.

Humans↗